Enhancing bioavailability of natural extracts for nutritional applications through dry powder inhalers (DPI) spray drying: technological advancements and future directions

Natural ingredients have many applications in modern medicine and pharmaceutical projects. However, they often have low solubility, poor chemical stability, and low bioavailability in vivo. Spray drying technology can overcome these challenges by enhancing the properties of natural ingredients. More...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Xiang, Jia, He, Binsheng, Tan, Songwen, Zhou, Wenhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354342/
https://www.ncbi.nlm.nih.gov/pubmed/37476406
http://dx.doi.org/10.3389/fnut.2023.1190912
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author Wang, Bo
Xiang, Jia
He, Binsheng
Tan, Songwen
Zhou, Wenhu
author_facet Wang, Bo
Xiang, Jia
He, Binsheng
Tan, Songwen
Zhou, Wenhu
author_sort Wang, Bo
collection PubMed
description Natural ingredients have many applications in modern medicine and pharmaceutical projects. However, they often have low solubility, poor chemical stability, and low bioavailability in vivo. Spray drying technology can overcome these challenges by enhancing the properties of natural ingredients. Moreover, drug delivery systems can be flexibly designed to optimize the performance of natural ingredients. Among the various drug delivery systems, dry powder inhalation (DPI) has attracted much attention in pharmaceutical research. Therefore, this review will focus on the spray drying of natural ingredients for DPI and discuss their synthesis and application.
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spelling pubmed-103543422023-07-20 Enhancing bioavailability of natural extracts for nutritional applications through dry powder inhalers (DPI) spray drying: technological advancements and future directions Wang, Bo Xiang, Jia He, Binsheng Tan, Songwen Zhou, Wenhu Front Nutr Nutrition Natural ingredients have many applications in modern medicine and pharmaceutical projects. However, they often have low solubility, poor chemical stability, and low bioavailability in vivo. Spray drying technology can overcome these challenges by enhancing the properties of natural ingredients. Moreover, drug delivery systems can be flexibly designed to optimize the performance of natural ingredients. Among the various drug delivery systems, dry powder inhalation (DPI) has attracted much attention in pharmaceutical research. Therefore, this review will focus on the spray drying of natural ingredients for DPI and discuss their synthesis and application. Frontiers Media S.A. 2023-07-05 /pmc/articles/PMC10354342/ /pubmed/37476406 http://dx.doi.org/10.3389/fnut.2023.1190912 Text en Copyright © 2023 Wang, Xiang, He, Tan and Zhou. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Wang, Bo
Xiang, Jia
He, Binsheng
Tan, Songwen
Zhou, Wenhu
Enhancing bioavailability of natural extracts for nutritional applications through dry powder inhalers (DPI) spray drying: technological advancements and future directions
title Enhancing bioavailability of natural extracts for nutritional applications through dry powder inhalers (DPI) spray drying: technological advancements and future directions
title_full Enhancing bioavailability of natural extracts for nutritional applications through dry powder inhalers (DPI) spray drying: technological advancements and future directions
title_fullStr Enhancing bioavailability of natural extracts for nutritional applications through dry powder inhalers (DPI) spray drying: technological advancements and future directions
title_full_unstemmed Enhancing bioavailability of natural extracts for nutritional applications through dry powder inhalers (DPI) spray drying: technological advancements and future directions
title_short Enhancing bioavailability of natural extracts for nutritional applications through dry powder inhalers (DPI) spray drying: technological advancements and future directions
title_sort enhancing bioavailability of natural extracts for nutritional applications through dry powder inhalers (dpi) spray drying: technological advancements and future directions
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354342/
https://www.ncbi.nlm.nih.gov/pubmed/37476406
http://dx.doi.org/10.3389/fnut.2023.1190912
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