Enhancement of CAR‐T cell activity against cholangiocarcinoma by simultaneous knockdown of six inhibitory membrane proteins

BACKGROUND: Existing treatments for cholangiocarcinoma have poor efficacy. However, chimeric antigen receptor‐T (CAR‐T) cells are emerging as a potential therapeutic strategy. Solid tumors possess multiple adverse factors in an immunosuppressive microenvironment that impair CAR‐T cell infiltration a...

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Detalles Bibliográficos
Autores principales: Qiao, Yidan, Chen, Jie, Wang, Xuemei, Yan, Shumei, Tan, Jizhou, Xia, Baijin, Chen, Yongjian, Lin, Keming, Zou, Fan, Liu, Bingfeng, He, Xin, Zhang, Yiwen, Zhang, Xu, Zhang, Hui, Wu, Xiangyuan, Lu, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354409/
https://www.ncbi.nlm.nih.gov/pubmed/37282786
http://dx.doi.org/10.1002/cac2.12452

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