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Enhancement of CAR‐T cell activity against cholangiocarcinoma by simultaneous knockdown of six inhibitory membrane proteins
BACKGROUND: Existing treatments for cholangiocarcinoma have poor efficacy. However, chimeric antigen receptor‐T (CAR‐T) cells are emerging as a potential therapeutic strategy. Solid tumors possess multiple adverse factors in an immunosuppressive microenvironment that impair CAR‐T cell infiltration a...
Główni autorzy: | , , , , , , , , , , , , , , , |
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Format: | Online Artykuł Texto |
Język: | English |
Wydane: |
John Wiley and Sons Inc.
2023
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Hasła przedmiotowe: | |
Dostęp online: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354409/ https://www.ncbi.nlm.nih.gov/pubmed/37282786 http://dx.doi.org/10.1002/cac2.12452 |