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EVMP: enhancing machine learning models for synthetic promoter strength prediction by Extended Vision Mutant Priority framework

INTRODUCTION: In metabolic engineering and synthetic biology applications, promoters with appropriate strengths are critical. However, it is time-consuming and laborious to annotate promoter strength by experiments. Nowadays, constructing mutation-based synthetic promoter libraries that span multipl...

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Detalles Bibliográficos
Autores principales: Yang, Weiqin, Li, Dexin, Huang, Ranran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354429/
https://www.ncbi.nlm.nih.gov/pubmed/37476664
http://dx.doi.org/10.3389/fmicb.2023.1215609