A novel murine model of pyoderma gangrenosum reveals that inflammatory skin-gut crosstalk is mediated by IL-1β-primed neutrophils

Pyoderma gangrenosum (PG) is a debilitating skin condition often accompanied by inflammatory bowel disease (IBD). Strikingly, ~40% of patients that present with PG have underlying IBD, suggesting shared but unknown mechanisms of pathogenesis. Impeding the development of effective treatments for PG i...

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Detalles Bibliográficos
Autores principales: Jatana, Samreen, Ponti, András K., Johnson, Erin E., Rebert, Nancy A., Smith, Jordyn L., Fulmer, Clifton G., Maytin, Edward V., Achkar, Jean-Paul, Fernandez, Anthony P., McDonald, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354730/
https://www.ncbi.nlm.nih.gov/pubmed/37475852
http://dx.doi.org/10.3389/fimmu.2023.1148893

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