Pitstop‐2 and its novel derivative RVD‐127 disrupt global cell dynamics and nuclear pores integrity by direct interaction with small GTPases

Clathrin‐mediated endocytosis (CME) is an essential cell physiological process of broad biomedical relevance. Since the recent introduction of Pitstop‐2 as a potent CME inhibitor, we and others have reported on substantial clathrin‐independent inhibitory effects. Herein, we developed and experimenta...

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Detalles Bibliográficos
Autores principales: Liashkovich, Ivan, Stefanello, Sílvio Terra, Vidyadharan, Reshma, Haufe, Günter, Erofeev, Alexander, Gorelkin, Peter V., Kolmogorov, Vasilii, Mizdal, Caren Rigon, Dulebo, Alexander, Bulk, Etmar, Kouzel, Ian U., Shahin, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354767/
https://www.ncbi.nlm.nih.gov/pubmed/37476059
http://dx.doi.org/10.1002/btm2.10425

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