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An iRGD‐conjugated photothermal therapy‐responsive gold nanoparticle system carrying siCDK7 induces necroptosis and immunotherapeutic responses in lung adenocarcinoma
Although immunotherapy has improved the clinical treatment of lung adenocarcinoma (LUAD), many tumors have poor responses to immunotherapy. In this study, we confirmed that high expression of Cyclin‐Dependent Kinase 7 (CDK7) promoted an immunosuppressive macrophage phenotype and macrophage infiltrat...
Autores principales: | Cai, Rui, Wang, Meng, Liu, Meiyuan, Zhu, Xiongjie, Feng, Longbao, Yu, Zhongjian, Yang, Xia, Zhang, Zhiwu, Guo, Huili, Guo, Rui, Zheng, Yanfang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354770/ https://www.ncbi.nlm.nih.gov/pubmed/37476070 http://dx.doi.org/10.1002/btm2.10430 |
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