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An iRGD‐conjugated photothermal therapy‐responsive gold nanoparticle system carrying siCDK7 induces necroptosis and immunotherapeutic responses in lung adenocarcinoma

Although immunotherapy has improved the clinical treatment of lung adenocarcinoma (LUAD), many tumors have poor responses to immunotherapy. In this study, we confirmed that high expression of Cyclin‐Dependent Kinase 7 (CDK7) promoted an immunosuppressive macrophage phenotype and macrophage infiltrat...

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Detalles Bibliográficos
Autores principales: Cai, Rui, Wang, Meng, Liu, Meiyuan, Zhu, Xiongjie, Feng, Longbao, Yu, Zhongjian, Yang, Xia, Zhang, Zhiwu, Guo, Huili, Guo, Rui, Zheng, Yanfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354770/
https://www.ncbi.nlm.nih.gov/pubmed/37476070
http://dx.doi.org/10.1002/btm2.10430

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