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Amino Chemoassay Profiling of Aromatic Aldehydes–Unraveling Drivers of Their Skin Sensitization Potency

[Image: see text] Aromatic aldehydes are ubiquitous in humans’ everyday life. As aldehydes, they can form imines (Schiff bases) with amino groups of skin proteins, leading to immune response-triggered allergic contact dermatitis. Many known aromatic aldehydes are considered as weak or nonsensitizers...

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Detalles Bibliográficos
Autores principales: Böhme, Alexander, Ulrich, Nadin, Schüürmann, Gerrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354803/
https://www.ncbi.nlm.nih.gov/pubmed/37315223
http://dx.doi.org/10.1021/acs.chemrestox.3c00013

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