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Inhibition of p90 ribosomal S6 kinases disrupts melanoma cell growth and immune evasion

BACKGROUND: The mitogen-activated protein kinase (MAPK) signaling pathway is frequently hyperactivated in malignant melanoma and its inhibition has proved to be an efficient treatment option for cases harboring BRAF(V600) mutations (BRAF(Mut)). However, there is still a significant need for effectiv...

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Detalles Bibliográficos
Autores principales:	Kosnopfel, Corinna, Wendlinger, Simone, Niessner, Heike, Siewert, Johannes, Sinnberg, Tobias, Hofmann, Angelika, Wohlfarth, Jonas, Schrama, David, Berthold, Marion, Siedel, Claudia, Sauer, Birgit, Jayanthan, Aarthi, Lenz, Georg, Dunn, Sandra E., Schilling, Bastian, Schittek, Birgit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354913/ https://www.ncbi.nlm.nih.gov/pubmed/37464364 http://dx.doi.org/10.1186/s13046-023-02755-5

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