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Inverse problem for parameters identification in a modified SIRD epidemic model using ensemble neural networks

In this paper, we propose a parameter identification methodology of the SIRD model, an extension of the classical SIR model, that considers the deceased as a separate category. In addition, our model includes one parameter which is the ratio between the real total number of infected and the number o...

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Autores principales: Petrica, Marian, Popescu, Ionel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354917/
https://www.ncbi.nlm.nih.gov/pubmed/37464258
http://dx.doi.org/10.1186/s13040-023-00337-x
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author Petrica, Marian
Popescu, Ionel
author_facet Petrica, Marian
Popescu, Ionel
author_sort Petrica, Marian
collection PubMed
description In this paper, we propose a parameter identification methodology of the SIRD model, an extension of the classical SIR model, that considers the deceased as a separate category. In addition, our model includes one parameter which is the ratio between the real total number of infected and the number of infected that were documented in the official statistics. Due to many factors, like governmental decisions, several variants circulating, opening and closing of schools, the typical assumption that the parameters of the model stay constant for long periods of time is not realistic. Thus our objective is to create a method which works for short periods of time. In this scope, we approach the estimation relying on the previous 7 days of data and then use the identified parameters to make predictions. To perform the estimation of the parameters we propose the average of an ensemble of neural networks. Each neural network is constructed based on a database built by solving the SIRD for 7 days, with random parameters. In this way, the networks learn the parameters from the solution of the SIRD model. Lastly we use the ensemble to get estimates of the parameters from the real data of Covid19 in Romania and then we illustrate the predictions for different periods of time, from 10 up to 45 days, for the number of deaths. The main goal was to apply this approach on the analysis of COVID-19 evolution in Romania, but this was also exemplified on other countries like Hungary, Czech Republic and Poland with similar results. The results are backed by a theorem which guarantees that we can recover the parameters of the model from the reported data. We believe this methodology can be used as a general tool for dealing with short term predictions of infectious diseases or in other compartmental models.
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spelling pubmed-103549172023-07-20 Inverse problem for parameters identification in a modified SIRD epidemic model using ensemble neural networks Petrica, Marian Popescu, Ionel BioData Min Research In this paper, we propose a parameter identification methodology of the SIRD model, an extension of the classical SIR model, that considers the deceased as a separate category. In addition, our model includes one parameter which is the ratio between the real total number of infected and the number of infected that were documented in the official statistics. Due to many factors, like governmental decisions, several variants circulating, opening and closing of schools, the typical assumption that the parameters of the model stay constant for long periods of time is not realistic. Thus our objective is to create a method which works for short periods of time. In this scope, we approach the estimation relying on the previous 7 days of data and then use the identified parameters to make predictions. To perform the estimation of the parameters we propose the average of an ensemble of neural networks. Each neural network is constructed based on a database built by solving the SIRD for 7 days, with random parameters. In this way, the networks learn the parameters from the solution of the SIRD model. Lastly we use the ensemble to get estimates of the parameters from the real data of Covid19 in Romania and then we illustrate the predictions for different periods of time, from 10 up to 45 days, for the number of deaths. The main goal was to apply this approach on the analysis of COVID-19 evolution in Romania, but this was also exemplified on other countries like Hungary, Czech Republic and Poland with similar results. The results are backed by a theorem which guarantees that we can recover the parameters of the model from the reported data. We believe this methodology can be used as a general tool for dealing with short term predictions of infectious diseases or in other compartmental models. BioMed Central 2023-07-18 /pmc/articles/PMC10354917/ /pubmed/37464258 http://dx.doi.org/10.1186/s13040-023-00337-x Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Petrica, Marian
Popescu, Ionel
Inverse problem for parameters identification in a modified SIRD epidemic model using ensemble neural networks
title Inverse problem for parameters identification in a modified SIRD epidemic model using ensemble neural networks
title_full Inverse problem for parameters identification in a modified SIRD epidemic model using ensemble neural networks
title_fullStr Inverse problem for parameters identification in a modified SIRD epidemic model using ensemble neural networks
title_full_unstemmed Inverse problem for parameters identification in a modified SIRD epidemic model using ensemble neural networks
title_short Inverse problem for parameters identification in a modified SIRD epidemic model using ensemble neural networks
title_sort inverse problem for parameters identification in a modified sird epidemic model using ensemble neural networks
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354917/
https://www.ncbi.nlm.nih.gov/pubmed/37464258
http://dx.doi.org/10.1186/s13040-023-00337-x
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