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Hypokalemia after rituximab administration in nephrotic syndrome: two case reports

Rituximab, a chimeric anti-CD20 monoclonal antibody, is an effective treatment for nephrotic syndrome. Hypokalemia is a rare adverse reaction among patients treated with rituximab although there have been extensive reports of acute and chronic adverse events with the administration of rituximab. We...

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Detalles Bibliográficos
Autores principales: Song, Yiyun, Ding, Lin, An, Xin, Zhao, Yi, Li, Xianhua, Yang, Xiangdong, Xiao, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354934/
https://www.ncbi.nlm.nih.gov/pubmed/37464309
http://dx.doi.org/10.1186/s12882-023-03079-4
Descripción
Sumario:Rituximab, a chimeric anti-CD20 monoclonal antibody, is an effective treatment for nephrotic syndrome. Hypokalemia is a rare adverse reaction among patients treated with rituximab although there have been extensive reports of acute and chronic adverse events with the administration of rituximab. We herein report two cases of symptomatic hypokalemia after intravenous rituximab administration in our center, to help health professionals consider the possibility of acute hypokalemia after rituximab administration, monitor potassium timely and develop an appropriate treatment plan.