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Histone deacetylase III interactions with BK polyomavirus large tumor antigen may affect protein stability

BACKGROUND: Human polyomavirus BK (BKPyV) causes associated nephropathy and contributes to urinary tract cancer development in renal transplant recipients. Large tumor antigen (LT) is an early protein essential in the polyomavirus life cycle. Protein acetylation plays a critical role in regulating p...

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Detalles Bibliográficos
Autores principales: Hsu, Yueh-Han, Chao, Chun-Nun, Huang, Hsin-Yi, Zhao, Pei-Wen, Hsu, Pang-Hung, Shen, Cheng-Huang, Chen, San-Yuan, Fang, Chiung-Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354968/
https://www.ncbi.nlm.nih.gov/pubmed/37464367
http://dx.doi.org/10.1186/s12985-023-02128-6

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