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Interferon alpha and beta receptor 1 knockout in human embryonic kidney 293 cells enhances the production efficiency of proteins or adenoviral vectors related to type I interferons

Human embryonic kidney (HEK) 293 cells are widely used in protein and viral vector production owing to their high transfection efficiency, rapid growth, and suspension growth capability. Given their antiviral, anticancer, and immune-enhancing effects, type I interferons (IFNs) have been used to prev...

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Detalles Bibliográficos
Autores principales: Kim, Aro, Park, Jong-Hyeon, Lee, Min Ja, Kim, Su-Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355049/
https://www.ncbi.nlm.nih.gov/pubmed/37476482
http://dx.doi.org/10.3389/fbioe.2023.1192291