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High-fat diet-disturbed gut microbiota-colonocyte interactions contribute to dysregulating peripheral tryptophan-kynurenine metabolism

BACKGROUND: Aberrant tryptophan (Trp)-kynurenine (Kyn) metabolism has been implicated in the pathogenesis of human disease. In particular, populations with long-term western-style diets are characterized by an excess of Kyn in the plasma. Host-gut microbiota interactions are dominated by diet and ar...

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Detalles Bibliográficos
Autores principales:	Sun, Penghao, Wang, Mengli, Liu, Yong-Xin, Li, Luqi, Chai, Xuejun, Zheng, Wei, Chen, Shulin, Zhu, Xiaoyan, Zhao, Shanting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355067/ https://www.ncbi.nlm.nih.gov/pubmed/37468922 http://dx.doi.org/10.1186/s40168-023-01606-x

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