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Fibronectin promotes tumor angiogenesis and progression of non-small-cell lung cancer by elevating WISP3 expression via FAK/MAPK/ HIF-1α axis and activating wnt signaling pathway

BACKGROUND: Fibronectin, an extracellular matrix protein, has been reported to be associated with heterogeneous cancer stemness, angiogenesis and progression in multiple cancer types. However, the roles and the underlying mechanism of fibronectin on the progression NSCLC need to be further elucidate...

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Detalles Bibliográficos
Autores principales: Zhou, Fei, Sun, Jianguo, Ye, Lingyun, Jiang, Tao, Li, Wei, Su, Chunxia, Ren, Shengxiang, Wu, Fengying, Zhou, Caicun, Gao, Guanghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355078/
https://www.ncbi.nlm.nih.gov/pubmed/37468964
http://dx.doi.org/10.1186/s40164-023-00419-w