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Anesthetic Considerations of Organ Procurement After Brain and Cardiac Death: A Narrative Review

Organ donation procedures have become more frequent in the US as the need for transplants is increasing. Defining the anesthesiologist's role in organ donations after brain and cardiac death is important, as is understanding its ethics and practical physiologic and perioperative implications. D...

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Autores principales: Brown, Michael B, Abramowicz, Apolonia E, Panzica, Peter J, Weber, Garret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355135/
https://www.ncbi.nlm.nih.gov/pubmed/37476138
http://dx.doi.org/10.7759/cureus.40629
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author Brown, Michael B
Abramowicz, Apolonia E
Panzica, Peter J
Weber, Garret
author_facet Brown, Michael B
Abramowicz, Apolonia E
Panzica, Peter J
Weber, Garret
author_sort Brown, Michael B
collection PubMed
description Organ donation procedures have become more frequent in the US as the need for transplants is increasing. Defining the anesthesiologist's role in organ donations after brain and cardiac death is important, as is understanding its ethics and practical physiologic and perioperative implications. Despite this, there are few papers specifically addressing the anesthetic management of organ donors. This review summarizes the preoperative, intraoperative, and postmortem considerations for the anesthesiologist involved in organ donation after either brain or cardiac death. A search of the published literature was performed using PubMed, Excerpta Medica dataBASE (EMBASE), and Google Scholar in March of 2022 for articles addressing anesthetic considerations of organ procurement surgeries after brain and cardiac death. This review demonstrates that anesthesiologists play a significant role in the organ procurement process. Their role in the perioperative management of the donor may affect the outcomes of organ transplantation. The gap between the number of organs harvested and the number of patients awaiting organ transplantation remains high despite continued efforts to increase the number of available organs. Perioperative management of organ donors aims at counteracting the associated unique physiologic derangements and targets optimization of oxygenation of the organs intended for procurement. Optimizing care after death can help ensure the viability of organs and the best outcomes for recipients. As organ donation after cardiac death (DCD) becomes more frequent in the US, anesthesiologists should be aware of the DCD classifications of donors and emerging novel perfusion techniques.
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spelling pubmed-103551352023-07-20 Anesthetic Considerations of Organ Procurement After Brain and Cardiac Death: A Narrative Review Brown, Michael B Abramowicz, Apolonia E Panzica, Peter J Weber, Garret Cureus Anesthesiology Organ donation procedures have become more frequent in the US as the need for transplants is increasing. Defining the anesthesiologist's role in organ donations after brain and cardiac death is important, as is understanding its ethics and practical physiologic and perioperative implications. Despite this, there are few papers specifically addressing the anesthetic management of organ donors. This review summarizes the preoperative, intraoperative, and postmortem considerations for the anesthesiologist involved in organ donation after either brain or cardiac death. A search of the published literature was performed using PubMed, Excerpta Medica dataBASE (EMBASE), and Google Scholar in March of 2022 for articles addressing anesthetic considerations of organ procurement surgeries after brain and cardiac death. This review demonstrates that anesthesiologists play a significant role in the organ procurement process. Their role in the perioperative management of the donor may affect the outcomes of organ transplantation. The gap between the number of organs harvested and the number of patients awaiting organ transplantation remains high despite continued efforts to increase the number of available organs. Perioperative management of organ donors aims at counteracting the associated unique physiologic derangements and targets optimization of oxygenation of the organs intended for procurement. Optimizing care after death can help ensure the viability of organs and the best outcomes for recipients. As organ donation after cardiac death (DCD) becomes more frequent in the US, anesthesiologists should be aware of the DCD classifications of donors and emerging novel perfusion techniques. Cureus 2023-06-19 /pmc/articles/PMC10355135/ /pubmed/37476138 http://dx.doi.org/10.7759/cureus.40629 Text en Copyright © 2023, Brown et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Anesthesiology
Brown, Michael B
Abramowicz, Apolonia E
Panzica, Peter J
Weber, Garret
Anesthetic Considerations of Organ Procurement After Brain and Cardiac Death: A Narrative Review
title Anesthetic Considerations of Organ Procurement After Brain and Cardiac Death: A Narrative Review
title_full Anesthetic Considerations of Organ Procurement After Brain and Cardiac Death: A Narrative Review
title_fullStr Anesthetic Considerations of Organ Procurement After Brain and Cardiac Death: A Narrative Review
title_full_unstemmed Anesthetic Considerations of Organ Procurement After Brain and Cardiac Death: A Narrative Review
title_short Anesthetic Considerations of Organ Procurement After Brain and Cardiac Death: A Narrative Review
title_sort anesthetic considerations of organ procurement after brain and cardiac death: a narrative review
topic Anesthesiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355135/
https://www.ncbi.nlm.nih.gov/pubmed/37476138
http://dx.doi.org/10.7759/cureus.40629
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