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miRNA/siRNA-directed pathway to produce noncoding piRNAs from endogenous protein-coding regions ensures Drosophila spermatogenesis

PIWI-interacting RNA (piRNA) pathways control transposable elements (TEs) and endogenous genes, playing important roles in animal gamete formation. However, the underlying piRNA biogenesis mechanisms remain elusive. Here, we show that endogenous protein coding sequences (CDSs), which are normally us...

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Detalles Bibliográficos
Autores principales:	Iki, Taichiro, Kawaguchi, Shinichi, Kai, Toshie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10355832/ https://www.ncbi.nlm.nih.gov/pubmed/37467338 http://dx.doi.org/10.1126/sciadv.adh0397

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