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The effect of restrictive fluid management on outcomes among geriatric hip fractures: a retrospective cohort study at five level I trauma centers
Restrictive fluid management (RFM) for hemodynamically unstable trauma patients has reduced mortality rates. The objective was to determine whether RFM benefits geriatric hip fracture patients, who are usually hemodynamically stable. DESIGN: Retrospective propensity-matched study. SETTING: Five Leve...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356122/ https://www.ncbi.nlm.nih.gov/pubmed/37475886 http://dx.doi.org/10.1097/OI9.0000000000000279 |
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author | Willis, Jordan Jarvis, Stephanie Berg, Gina M. Corrigan, Chad Madayag, Robert Reynolds, Cassandra Tanner, Allen Marshall, Gary Palacio Lascano, Carlos Bar-Or, David |
author_facet | Willis, Jordan Jarvis, Stephanie Berg, Gina M. Corrigan, Chad Madayag, Robert Reynolds, Cassandra Tanner, Allen Marshall, Gary Palacio Lascano, Carlos Bar-Or, David |
author_sort | Willis, Jordan |
collection | PubMed |
description | Restrictive fluid management (RFM) for hemodynamically unstable trauma patients has reduced mortality rates. The objective was to determine whether RFM benefits geriatric hip fracture patients, who are usually hemodynamically stable. DESIGN: Retrospective propensity-matched study. SETTING: Five Level I trauma centers (January 1, 2018–December 12, 2018). PATIENTS: Geriatric patients (65 years or older) with hip fractures were included in this study. Patients with multiple injuries, nonoperative management, and preoperative blood products were excluded. INTERVENTION: Patients were grouped by fluid volume (normal saline, lactated Ringer, dextrose, electrolytes, and medications) received preoperatively or ≤24 hours of arrival; patients with standard fluid management (SFM) received ≥150 mL and RFM <150 mL of fluids. MAIN OUTCOME MEASUREMENTS: The primary outcomes were length of stay (LOS), delayed ambulation (>2 days postoperatively), and mortality. Paired Student t-tests, Wilcoxon paired rank sum tests, and McNemar tests were used; an α value of < 0.05 was considered statistically significant. RESULTS: There were 523 patients (40% RFM, 60% SFM); after matching, there were 95 patients per arm. The matched patients were well-balanced, including no difference in time from arrival to surgery. RFM and SFM patients received a median of 80 mL and 1250 mL of preoperative fluids, respectively (P < 0.001). Postoperative fluid volumes were 1550 versus 2000 mL, respectively, (P = 0.73), and LOSs were similar between the two groups (5 versus 5 days, P = 0.83). Mortality and complications, including acute kidney injuries, were similar. Delayed ambulation rates were similar overall. When stratified by preinjury ambulation status, SFM was associated with delayed ambulation for patients not walking independently before injury (P = 0.01), but RFM was not (P = 0.09). CONCLUSIONS: RFM seems to be safe in terms of laboratory results, complications, and disposition. SFM may lead to delayed ambulation for patients who are not walking independently before injury. |
format | Online Article Text |
id | pubmed-10356122 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Wolters Kluwer |
record_format | MEDLINE/PubMed |
spelling | pubmed-103561222023-07-20 The effect of restrictive fluid management on outcomes among geriatric hip fractures: a retrospective cohort study at five level I trauma centers Willis, Jordan Jarvis, Stephanie Berg, Gina M. Corrigan, Chad Madayag, Robert Reynolds, Cassandra Tanner, Allen Marshall, Gary Palacio Lascano, Carlos Bar-Or, David OTA Int Clinical/Basic Science Research Article Restrictive fluid management (RFM) for hemodynamically unstable trauma patients has reduced mortality rates. The objective was to determine whether RFM benefits geriatric hip fracture patients, who are usually hemodynamically stable. DESIGN: Retrospective propensity-matched study. SETTING: Five Level I trauma centers (January 1, 2018–December 12, 2018). PATIENTS: Geriatric patients (65 years or older) with hip fractures were included in this study. Patients with multiple injuries, nonoperative management, and preoperative blood products were excluded. INTERVENTION: Patients were grouped by fluid volume (normal saline, lactated Ringer, dextrose, electrolytes, and medications) received preoperatively or ≤24 hours of arrival; patients with standard fluid management (SFM) received ≥150 mL and RFM <150 mL of fluids. MAIN OUTCOME MEASUREMENTS: The primary outcomes were length of stay (LOS), delayed ambulation (>2 days postoperatively), and mortality. Paired Student t-tests, Wilcoxon paired rank sum tests, and McNemar tests were used; an α value of < 0.05 was considered statistically significant. RESULTS: There were 523 patients (40% RFM, 60% SFM); after matching, there were 95 patients per arm. The matched patients were well-balanced, including no difference in time from arrival to surgery. RFM and SFM patients received a median of 80 mL and 1250 mL of preoperative fluids, respectively (P < 0.001). Postoperative fluid volumes were 1550 versus 2000 mL, respectively, (P = 0.73), and LOSs were similar between the two groups (5 versus 5 days, P = 0.83). Mortality and complications, including acute kidney injuries, were similar. Delayed ambulation rates were similar overall. When stratified by preinjury ambulation status, SFM was associated with delayed ambulation for patients not walking independently before injury (P = 0.01), but RFM was not (P = 0.09). CONCLUSIONS: RFM seems to be safe in terms of laboratory results, complications, and disposition. SFM may lead to delayed ambulation for patients who are not walking independently before injury. Wolters Kluwer 2023-07-19 /pmc/articles/PMC10356122/ /pubmed/37475886 http://dx.doi.org/10.1097/OI9.0000000000000279 Text en Copyright © 2023 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Orthopaedic Trauma Association. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Clinical/Basic Science Research Article Willis, Jordan Jarvis, Stephanie Berg, Gina M. Corrigan, Chad Madayag, Robert Reynolds, Cassandra Tanner, Allen Marshall, Gary Palacio Lascano, Carlos Bar-Or, David The effect of restrictive fluid management on outcomes among geriatric hip fractures: a retrospective cohort study at five level I trauma centers |
title | The effect of restrictive fluid management on outcomes among geriatric hip fractures: a retrospective cohort study at five level I trauma centers |
title_full | The effect of restrictive fluid management on outcomes among geriatric hip fractures: a retrospective cohort study at five level I trauma centers |
title_fullStr | The effect of restrictive fluid management on outcomes among geriatric hip fractures: a retrospective cohort study at five level I trauma centers |
title_full_unstemmed | The effect of restrictive fluid management on outcomes among geriatric hip fractures: a retrospective cohort study at five level I trauma centers |
title_short | The effect of restrictive fluid management on outcomes among geriatric hip fractures: a retrospective cohort study at five level I trauma centers |
title_sort | effect of restrictive fluid management on outcomes among geriatric hip fractures: a retrospective cohort study at five level i trauma centers |
topic | Clinical/Basic Science Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356122/ https://www.ncbi.nlm.nih.gov/pubmed/37475886 http://dx.doi.org/10.1097/OI9.0000000000000279 |
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