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Microcalorimetry reveals multi-state thermal denaturation of G. stearothermophilus tryptophanyl-tRNA synthetase

Mechanistic studies of Geobacillus stearothermophilus tryptophanyl-tRNA synthetase (TrpRS) afford an unusually detailed description—the escapement mechanism—for the distinct steps coupling catalysis to domain motion, efficiently converting the free energy of ATP hydrolysis into biologically useful a...

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Detalles Bibliográficos
Autores principales:	Chandrasekaran, Srinivas Niranj, Das, Jhuma, Dokholyan, Nikolay V., Carter, Charles W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Crystallographic Association 2023
Materias:	ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356175/ https://www.ncbi.nlm.nih.gov/pubmed/37476003 http://dx.doi.org/10.1063/4.0000181

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