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Autonomous action and cooperativity between the ONECUT2 transcription factor and its 3′ untranslated region

The transcription factor ONECUT2 (OC2) is a master transcriptional regulator operating in metastatic castration-resistant prostate cancer that suppresses androgen receptor activity and promotes neural differentiation and tumor cell survival. OC2 mRNA possesses an unusually long (14,575 nt), evolutio...

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Detalles Bibliográficos
Autores principales: Steadman, Kenneth, You, Sungyong, Srinivas, Dustin V., Mouakkad, Lila, Yan, Yiwu, Kim, Minhyung, Venugopal, Smrruthi V., Tanaka, Hisashi, Freeman, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356556/
https://www.ncbi.nlm.nih.gov/pubmed/37484909
http://dx.doi.org/10.3389/fcell.2023.1206259