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Autonomous action and cooperativity between the ONECUT2 transcription factor and its 3′ untranslated region
The transcription factor ONECUT2 (OC2) is a master transcriptional regulator operating in metastatic castration-resistant prostate cancer that suppresses androgen receptor activity and promotes neural differentiation and tumor cell survival. OC2 mRNA possesses an unusually long (14,575 nt), evolutio...
Autores principales: | Steadman, Kenneth, You, Sungyong, Srinivas, Dustin V., Mouakkad, Lila, Yan, Yiwu, Kim, Minhyung, Venugopal, Smrruthi V., Tanaka, Hisashi, Freeman, Michael R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356556/ https://www.ncbi.nlm.nih.gov/pubmed/37484909 http://dx.doi.org/10.3389/fcell.2023.1206259 |
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