Visceral adipose tissue secretome from early and late-stage oesophageal cancer patients differentially affects effector and regulatory T cells

AIM: Visceral obesity is a key risk factor in the development of oesophagogastric junctional adenocarcinoma (OGJ), predominantly via generation of systemic low grade inflammation. Obesity-induced inflammation promotes resistance to current standards of care, enhancing tumour cell growth and survival...

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Detalles Bibliográficos
Autores principales: Davern, Maria, Bracken-Clarke, Dara, Donlon, Noel E., Sheppard, Andrew D., Connell, Fiona O’, Heeran, Aisling B., Majcher, Klaudia, Conroy, Melissa J., Mylod, Eimear, Butler, Christine, Donohoe, Claire, Donnell, Dearbhaile O’, Lowery, Maeve, Bhardwaj, Anshul, Ravi, Narayanasamy, Melo, Ashanty A., Sullivan, Jacintha O’, Reynolds, John V., Lysaght, Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356656/
https://www.ncbi.nlm.nih.gov/pubmed/36790524
http://dx.doi.org/10.1007/s00432-023-04620-6

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