von Willebrand factor-binding protein (vWbp)-activated factor XIII and transglutaminase 2 (TG2) promote cross-linking between FnBPA from Staphylococcus aureus and fibrinogen

The secreted von Willebrand factor-binding protein (vWbp) from Staphylococcus aureus interacts with the coagulation factors prothrombin and fibrinogen (Fbg), leading to the non-proteolytic transglutaminase activation of Factor XIII (FXIII). In this study we found that vWbp-activated FXIII catalyses...

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Detalles Bibliográficos
Autores principales: Motta, Chiara, Pellegrini, Angelica, Camaione, Stefano, Geoghegan, Joan, Speziale, Pietro, Barbieri, Giulia, Pietrocola, Giampiero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356753/
https://www.ncbi.nlm.nih.gov/pubmed/37468579
http://dx.doi.org/10.1038/s41598-023-38972-3

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