Mutations observed in somatic evolution reveal underlying gene mechanisms

Highly sensitive DNA sequencing techniques have allowed the discovery of large numbers of somatic mutations in normal tissues. Some mutations confer a competitive advantage over wild-type cells, generating expanding clones that spread through the tissue. Competition between mutant clones leads to se...

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Detalles Bibliográficos
Autores principales: Hall, Michael W. J., Shorthouse, David, Alcraft, Rachel, Jones, Philip H., Hall, Benjamin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356810/
https://www.ncbi.nlm.nih.gov/pubmed/37468606
http://dx.doi.org/10.1038/s42003-023-05136-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356810/
https://www.ncbi.nlm.nih.gov/pubmed/37468606
http://dx.doi.org/10.1038/s42003-023-05136-y

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