Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B(12) delivery and repair

G-proteins function as molecular switches to power cofactor translocation and confer fidelity in metal trafficking. The G-protein, MMAA, together with MMAB, an adenosyltransferase, orchestrate cofactor delivery and repair of B(12)-dependent human methylmalonyl-CoA mutase (MMUT). The mechanism by whi...

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Detalles Bibliográficos
Autores principales: Mascarenhas, Romila, Ruetz, Markus, Gouda, Harsha, Heitman, Natalie, Yaw, Madeline, Banerjee, Ruma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356863/
https://www.ncbi.nlm.nih.gov/pubmed/37468522
http://dx.doi.org/10.1038/s41467-023-40077-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356863/
https://www.ncbi.nlm.nih.gov/pubmed/37468522
http://dx.doi.org/10.1038/s41467-023-40077-4

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