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Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B(12) delivery and repair
G-proteins function as molecular switches to power cofactor translocation and confer fidelity in metal trafficking. The G-protein, MMAA, together with MMAB, an adenosyltransferase, orchestrate cofactor delivery and repair of B(12)-dependent human methylmalonyl-CoA mutase (MMUT). The mechanism by whi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356863/ https://www.ncbi.nlm.nih.gov/pubmed/37468522 http://dx.doi.org/10.1038/s41467-023-40077-4 |