Increased glutamate and glutamine levels and their relationship to astrocytes and dopaminergic transmissions in the brains of adults with autism

Increased excitatory neuronal tones have been implicated in autism, but its mechanism remains elusive. The amplified glutamate signals may arise from enhanced glutamatergic circuits, which can be affected by astrocyte activation and suppressive signaling of dopamine neurotransmission. We tested this...

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Detalles Bibliográficos
Autores principales: Oya, Masaki, Matsuoka, Kiwamu, Kubota, Manabu, Fujino, Junya, Tei, Shisei, Takahata, Keisuke, Tagai, Kenji, Yamamoto, Yasuharu, Shimada, Hitoshi, Seki, Chie, Itahashi, Takashi, Aoki, Yuta Y., Ohta, Haruhisa, Hashimoto, Ryu-ichiro, Sugihara, Genichi, Obata, Takayuki, Zhang, Ming-Rong, Suhara, Tetsuya, Nakamura, Motoaki, Kato, Nobumasa, Takado, Yuhei, Takahashi, Hidehiko, Higuchi, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356952/
https://www.ncbi.nlm.nih.gov/pubmed/37468523
http://dx.doi.org/10.1038/s41598-023-38306-3

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