Reply: Confounding in Mendelian randomisation studies

Mendelian randomisation (MR) overcomes classical confounding issues that beset observational studies. “Horizontal” but not “vertical” pleiotropy can bias MR study findings but we found no evidence that it was present in our MR analysis of GORD on IPF. https://bit.ly/3Jn7aeq

Detalles Bibliográficos
Autores principales: Reynolds, Carl J., Minelli, Cosetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2023
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356965/
https://www.ncbi.nlm.nih.gov/pubmed/37474152
http://dx.doi.org/10.1183/13993003.00995-2023
Descripción
Sumario:Mendelian randomisation (MR) overcomes classical confounding issues that beset observational studies. “Horizontal” but not “vertical” pleiotropy can bias MR study findings but we found no evidence that it was present in our MR analysis of GORD on IPF. https://bit.ly/3Jn7aeq

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