Reply: Confounding in Mendelian randomisation studies

Mendelian randomisation (MR) overcomes classical confounding issues that beset observational studies. “Horizontal” but not “vertical” pleiotropy can bias MR study findings but we found no evidence that it was present in our MR analysis of GORD on IPF. https://bit.ly/3Jn7aeq

Detalles Bibliográficos
Autores principales: Reynolds, Carl J., Minelli, Cosetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2023
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356965/
https://www.ncbi.nlm.nih.gov/pubmed/37474152
http://dx.doi.org/10.1183/13993003.00995-2023
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author Reynolds, Carl J.
Minelli, Cosetta
author_facet Reynolds, Carl J.
Minelli, Cosetta
author_sort Reynolds, Carl J.
collection PubMed
description Mendelian randomisation (MR) overcomes classical confounding issues that beset observational studies. “Horizontal” but not “vertical” pleiotropy can bias MR study findings but we found no evidence that it was present in our MR analysis of GORD on IPF. https://bit.ly/3Jn7aeq
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spelling pubmed-103569652023-07-21 Reply: Confounding in Mendelian randomisation studies Reynolds, Carl J. Minelli, Cosetta Eur Respir J Correspondence Mendelian randomisation (MR) overcomes classical confounding issues that beset observational studies. “Horizontal” but not “vertical” pleiotropy can bias MR study findings but we found no evidence that it was present in our MR analysis of GORD on IPF. https://bit.ly/3Jn7aeq European Respiratory Society 2023-07-20 /pmc/articles/PMC10356965/ /pubmed/37474152 http://dx.doi.org/10.1183/13993003.00995-2023 Text en Copyright ©The authors 2023. https://creativecommons.org/licenses/by/4.0/This version is distributed under the terms of the Creative Commons Attribution Licence 4.0.
spellingShingle Correspondence
Reynolds, Carl J.
Minelli, Cosetta
Reply: Confounding in Mendelian randomisation studies
title Reply: Confounding in Mendelian randomisation studies
title_full Reply: Confounding in Mendelian randomisation studies
title_fullStr Reply: Confounding in Mendelian randomisation studies
title_full_unstemmed Reply: Confounding in Mendelian randomisation studies
title_short Reply: Confounding in Mendelian randomisation studies
title_sort reply: confounding in mendelian randomisation studies
topic Correspondence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356965/
https://www.ncbi.nlm.nih.gov/pubmed/37474152
http://dx.doi.org/10.1183/13993003.00995-2023
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