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Mechanisms of hypoxaemia in severe pulmonary hypertension associated with COPD

Severe hypoxaemia, characteristic of COPD with severe pulmonary hypertension, is due to a combination of greater ventilation–perfusion mismatch, increased intrapulmonary shunt and reduced P(vO(2)), with negligible hypoxic pulmonary vasoconstriction regulation https://bit.ly/3Wnzpik

Detalles Bibliográficos
Autores principales: Piccari, Lucilla, Blanco, Isabel, Torralba, Yolanda, Arismendi, Ebymar, Gistau, Concepción, Ramírez, Ana, Gimeno-Santos, Elena, Roca, Josep, Burgos, Felip, Rodríguez-Roisín, Roberto, Barberà, Joan Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10356966/
https://www.ncbi.nlm.nih.gov/pubmed/37414421
http://dx.doi.org/10.1183/13993003.00463-2023
Descripción
Sumario:Severe hypoxaemia, characteristic of COPD with severe pulmonary hypertension, is due to a combination of greater ventilation–perfusion mismatch, increased intrapulmonary shunt and reduced P(vO(2)), with negligible hypoxic pulmonary vasoconstriction regulation https://bit.ly/3Wnzpik