Pamrevlumab, a Fully Human Monoclonal Antibody Targeting Connective Tissue Growth Factor, for Non-Ambulatory Patients with Duchenne Muscular Dystrophy

BACKGROUND: Duchenne muscular dystrophy (DMD) is a neuromuscular disease stemming from dystrophin gene mutations. Lack of dystrophin leads to progressive muscle damage and replacement of muscle with fibrotic and adipose tissue. Pamrevlumab (FG-3019), a fully human monoclonal antibody that binds to c...

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Detalles Bibliográficos
Autores principales: Connolly, Anne M., Zaidman, Craig M., Brandsema, John F., Phan, Han C., Tian, Cuixia, Zhang, Xueping, Li, Jack, Eisner, Mark D., Carrier, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357134/
https://www.ncbi.nlm.nih.gov/pubmed/37248912
http://dx.doi.org/10.3233/JND-230019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357134/
https://www.ncbi.nlm.nih.gov/pubmed/37248912
http://dx.doi.org/10.3233/JND-230019

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