Generation and Characterization of the First Murine Model of Alzheimer’s Disease with Mutated AβPP Inserted in a BALB/c Background (C.B6/J-APP(swe))

BACKGROUND: Numerous mouse models of Alzheimer’s disease (AD) are available, but all suffer from certain limitations, thus prompting further attempts. To date, no one model exists with amyloidopathy in a BALB/c strain. OBJECTIVE: To generate and characterize the C.B6/J-APP(swe) mouse, a model of AD...

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Detalles Bibliográficos
Autores principales: Balietti, Marta, Casoli, Tiziana, Giorgetti, Belinda, Colangeli, Roberto, Nicoletti, Cristina, Solazzi, Moreno, Pugliese, Arianna, Conti, Fiorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357192/
https://www.ncbi.nlm.nih.gov/pubmed/37182890
http://dx.doi.org/10.3233/JAD-230195

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