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Non-viral approaches for gene therapy and therapeutic genome editing across the blood–brain barrier

The success of brain-targeted gene therapy and therapeutic genome editing hinges on the efficient delivery of biologics bypassing the blood–brain barrier (BBB), which presents a significant challenge in the development of treatments for central nervous system disorders. This is particularly the case...

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Detalles Bibliográficos
Autores principales: Xie, Ruosen, Wang, Yuyuan, Burger, Jacobus C., Li, Dongdong, Zhu, Min, Gong, Shaoqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357415/
https://www.ncbi.nlm.nih.gov/pubmed/37485250
http://dx.doi.org/10.1007/s44258-023-00004-0