Deep Learning Approach for the Discovery of Tumor-Targeting Small Organic Ligands from DNA-Encoded Chemical Libraries

[Image: see text] DNA-Encoded Chemical Libraries (DELs) have emerged as efficient and cost-effective ligand discovery tools, which enable the generation of protein–ligand interaction data of unprecedented size. In this article, we present an approach that combines DEL screening and instance-level de...

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Detalles Bibliográficos
Autores principales: Torng, Wen, Biancofiore, Ilaria, Oehler, Sebastian, Xu, Jin, Xu, Jessica, Watson, Ian, Masina, Brenno, Prati, Luca, Favalli, Nicholas, Bassi, Gabriele, Neri, Dario, Cazzamalli, Samuele, Feng, Jianwen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357458/
https://www.ncbi.nlm.nih.gov/pubmed/37483198
http://dx.doi.org/10.1021/acsomega.3c01775

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