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Metastatic renal cell carcinoma to the small bowel 6 years postnephrectomy

Renal cell carcinoma (RCC) is an unpredictable malignancy, with 25%–30% of patients developing metastatic disease. The most common sites of metastasis are the lung, bones, liver and brain, with small intestine metastasis being minimally reported in the literature. This report describes a case of sma...

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Autores principales: Kim, David, Reed, Gasinee, Ellis, Kelsey Kay, Loden, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357641/
https://www.ncbi.nlm.nih.gov/pubmed/37463780
http://dx.doi.org/10.1136/bcr-2023-254939
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author Kim, David
Reed, Gasinee
Ellis, Kelsey Kay
Loden, Jason
author_facet Kim, David
Reed, Gasinee
Ellis, Kelsey Kay
Loden, Jason
author_sort Kim, David
collection PubMed
description Renal cell carcinoma (RCC) is an unpredictable malignancy, with 25%–30% of patients developing metastatic disease. The most common sites of metastasis are the lung, bones, liver and brain, with small intestine metastasis being minimally reported in the literature. This report describes a case of small bowel obstruction caused by metastatic RCC in a male patient in his 60 s who had previously undergone a radical nephrectomy with adjuvant pembrolizumab therapy 6 years prior. The patient underwent a diagnostic laparoscopy converted to a laparotomy due to the complexity of the case. During surgical exploration, an enterectomy and end-to-end anastomosis were performed. This case emphasises the possibility of RCC metastasising to the small intestine, which may present with small bowel obstruction, while highlighting the importance of patient education for early detection to improve prognosis. Additionally, this report discusses treatment options for managing RCC metastasis to the small intestine.
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spelling pubmed-103576412023-07-21 Metastatic renal cell carcinoma to the small bowel 6 years postnephrectomy Kim, David Reed, Gasinee Ellis, Kelsey Kay Loden, Jason BMJ Case Rep Case Reports: Rare disease Renal cell carcinoma (RCC) is an unpredictable malignancy, with 25%–30% of patients developing metastatic disease. The most common sites of metastasis are the lung, bones, liver and brain, with small intestine metastasis being minimally reported in the literature. This report describes a case of small bowel obstruction caused by metastatic RCC in a male patient in his 60 s who had previously undergone a radical nephrectomy with adjuvant pembrolizumab therapy 6 years prior. The patient underwent a diagnostic laparoscopy converted to a laparotomy due to the complexity of the case. During surgical exploration, an enterectomy and end-to-end anastomosis were performed. This case emphasises the possibility of RCC metastasising to the small intestine, which may present with small bowel obstruction, while highlighting the importance of patient education for early detection to improve prognosis. Additionally, this report discusses treatment options for managing RCC metastasis to the small intestine. BMJ Publishing Group 2023-07-18 /pmc/articles/PMC10357641/ /pubmed/37463780 http://dx.doi.org/10.1136/bcr-2023-254939 Text en © BMJ Publishing Group Limited 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Case Reports: Rare disease
Kim, David
Reed, Gasinee
Ellis, Kelsey Kay
Loden, Jason
Metastatic renal cell carcinoma to the small bowel 6 years postnephrectomy
title Metastatic renal cell carcinoma to the small bowel 6 years postnephrectomy
title_full Metastatic renal cell carcinoma to the small bowel 6 years postnephrectomy
title_fullStr Metastatic renal cell carcinoma to the small bowel 6 years postnephrectomy
title_full_unstemmed Metastatic renal cell carcinoma to the small bowel 6 years postnephrectomy
title_short Metastatic renal cell carcinoma to the small bowel 6 years postnephrectomy
title_sort metastatic renal cell carcinoma to the small bowel 6 years postnephrectomy
topic Case Reports: Rare disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357641/
https://www.ncbi.nlm.nih.gov/pubmed/37463780
http://dx.doi.org/10.1136/bcr-2023-254939
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