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Metastatic renal cell carcinoma to the small bowel 6 years postnephrectomy
Renal cell carcinoma (RCC) is an unpredictable malignancy, with 25%–30% of patients developing metastatic disease. The most common sites of metastasis are the lung, bones, liver and brain, with small intestine metastasis being minimally reported in the literature. This report describes a case of sma...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357641/ https://www.ncbi.nlm.nih.gov/pubmed/37463780 http://dx.doi.org/10.1136/bcr-2023-254939 |
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author | Kim, David Reed, Gasinee Ellis, Kelsey Kay Loden, Jason |
author_facet | Kim, David Reed, Gasinee Ellis, Kelsey Kay Loden, Jason |
author_sort | Kim, David |
collection | PubMed |
description | Renal cell carcinoma (RCC) is an unpredictable malignancy, with 25%–30% of patients developing metastatic disease. The most common sites of metastasis are the lung, bones, liver and brain, with small intestine metastasis being minimally reported in the literature. This report describes a case of small bowel obstruction caused by metastatic RCC in a male patient in his 60 s who had previously undergone a radical nephrectomy with adjuvant pembrolizumab therapy 6 years prior. The patient underwent a diagnostic laparoscopy converted to a laparotomy due to the complexity of the case. During surgical exploration, an enterectomy and end-to-end anastomosis were performed. This case emphasises the possibility of RCC metastasising to the small intestine, which may present with small bowel obstruction, while highlighting the importance of patient education for early detection to improve prognosis. Additionally, this report discusses treatment options for managing RCC metastasis to the small intestine. |
format | Online Article Text |
id | pubmed-10357641 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-103576412023-07-21 Metastatic renal cell carcinoma to the small bowel 6 years postnephrectomy Kim, David Reed, Gasinee Ellis, Kelsey Kay Loden, Jason BMJ Case Rep Case Reports: Rare disease Renal cell carcinoma (RCC) is an unpredictable malignancy, with 25%–30% of patients developing metastatic disease. The most common sites of metastasis are the lung, bones, liver and brain, with small intestine metastasis being minimally reported in the literature. This report describes a case of small bowel obstruction caused by metastatic RCC in a male patient in his 60 s who had previously undergone a radical nephrectomy with adjuvant pembrolizumab therapy 6 years prior. The patient underwent a diagnostic laparoscopy converted to a laparotomy due to the complexity of the case. During surgical exploration, an enterectomy and end-to-end anastomosis were performed. This case emphasises the possibility of RCC metastasising to the small intestine, which may present with small bowel obstruction, while highlighting the importance of patient education for early detection to improve prognosis. Additionally, this report discusses treatment options for managing RCC metastasis to the small intestine. BMJ Publishing Group 2023-07-18 /pmc/articles/PMC10357641/ /pubmed/37463780 http://dx.doi.org/10.1136/bcr-2023-254939 Text en © BMJ Publishing Group Limited 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | Case Reports: Rare disease Kim, David Reed, Gasinee Ellis, Kelsey Kay Loden, Jason Metastatic renal cell carcinoma to the small bowel 6 years postnephrectomy |
title | Metastatic renal cell carcinoma to the small bowel 6 years postnephrectomy |
title_full | Metastatic renal cell carcinoma to the small bowel 6 years postnephrectomy |
title_fullStr | Metastatic renal cell carcinoma to the small bowel 6 years postnephrectomy |
title_full_unstemmed | Metastatic renal cell carcinoma to the small bowel 6 years postnephrectomy |
title_short | Metastatic renal cell carcinoma to the small bowel 6 years postnephrectomy |
title_sort | metastatic renal cell carcinoma to the small bowel 6 years postnephrectomy |
topic | Case Reports: Rare disease |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357641/ https://www.ncbi.nlm.nih.gov/pubmed/37463780 http://dx.doi.org/10.1136/bcr-2023-254939 |
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