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GAS6-based CAR-T cells exhibit potent antitumor activity against pancreatic cancer

BACKGROUND: The receptor tyrosine kinases TAM family (TYRO3, AXL, and MERTK) are highly expressed in multiple forms of cancer cells and tumor-associated macrophages and promote the development of cancers including pancreatic tumor. Targeting TAM receptors could be a promising therapeutic option. MET...

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Detalles Bibliográficos
Autores principales:	Fan, Jiawei, Yu, Ye, Yan, Lanzhen, Yuan, Yuncang, Sun, Bin, Yang, Dong, Liu, Nan, Guo, Jing, Zhang, Jie, Zhao, Xudong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357739/ https://www.ncbi.nlm.nih.gov/pubmed/37475048 http://dx.doi.org/10.1186/s13045-023-01467-9

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