Cargando…

Interstitial lung disease related to occupational hard metal exposure: two case reports

BACKGROUND: Hard metal lung disease (HMLD) is a relatively less known occupational interstitial lung disease, and instances of HMLD resulting from para-occupational exposure are rarely reported. CASE PRESENTATION: This paper presents two cases of interstitial lung disease caused by exposure to hard...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, I-Fan, Shen, Hsiao-Chin, Lin, Shiou-Fu, Chang, Ho-Chuen, Chen, Tzu-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357746/
https://www.ncbi.nlm.nih.gov/pubmed/37468982
http://dx.doi.org/10.1186/s13256-023-04043-4
_version_ 1785075561109913600
author Lin, I-Fan
Shen, Hsiao-Chin
Lin, Shiou-Fu
Chang, Ho-Chuen
Chen, Tzu-Tao
author_facet Lin, I-Fan
Shen, Hsiao-Chin
Lin, Shiou-Fu
Chang, Ho-Chuen
Chen, Tzu-Tao
author_sort Lin, I-Fan
collection PubMed
description BACKGROUND: Hard metal lung disease (HMLD) is a relatively less known occupational interstitial lung disease, and instances of HMLD resulting from para-occupational exposure are rarely reported. CASE PRESENTATION: This paper presents two cases of interstitial lung disease caused by exposure to hard metal. The first case involves a 37-year-old Taiwanese man who had worked at a grinder station for hard metal materials for 12 years without respiratory protective equipment. He experienced a dry cough and exertional dyspnea, and his chest imaging and pathology findings were consistent with the features of usual interstitial pneumonia. Analysis of his lung tissue revealed the presence of tungsten and cobalt. The second case involves a 68-year-old Taiwanese woman, the mother of the first patient, who had hand-washed her son’s workwear. She experienced a dry cough and had similar imaging findings to her son. After her son left his job, they both exhibited improved symptoms and lung functions with nintedanib treatment. These findings suggest a diagnosis of HMLD and interstitial lung disease resulting from para-occupational exposure to hard metal dust. CONCLUSIONS: The diagnosis of HMLD relies on obtaining a detailed occupational exposure history. If HMLD is diagnosed, discontinuing exposing to hard metal dusts can lead to improved lung function. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13256-023-04043-4.
format Online
Article
Text
id pubmed-10357746
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-103577462023-07-21 Interstitial lung disease related to occupational hard metal exposure: two case reports Lin, I-Fan Shen, Hsiao-Chin Lin, Shiou-Fu Chang, Ho-Chuen Chen, Tzu-Tao J Med Case Rep Case Report BACKGROUND: Hard metal lung disease (HMLD) is a relatively less known occupational interstitial lung disease, and instances of HMLD resulting from para-occupational exposure are rarely reported. CASE PRESENTATION: This paper presents two cases of interstitial lung disease caused by exposure to hard metal. The first case involves a 37-year-old Taiwanese man who had worked at a grinder station for hard metal materials for 12 years without respiratory protective equipment. He experienced a dry cough and exertional dyspnea, and his chest imaging and pathology findings were consistent with the features of usual interstitial pneumonia. Analysis of his lung tissue revealed the presence of tungsten and cobalt. The second case involves a 68-year-old Taiwanese woman, the mother of the first patient, who had hand-washed her son’s workwear. She experienced a dry cough and had similar imaging findings to her son. After her son left his job, they both exhibited improved symptoms and lung functions with nintedanib treatment. These findings suggest a diagnosis of HMLD and interstitial lung disease resulting from para-occupational exposure to hard metal dust. CONCLUSIONS: The diagnosis of HMLD relies on obtaining a detailed occupational exposure history. If HMLD is diagnosed, discontinuing exposing to hard metal dusts can lead to improved lung function. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13256-023-04043-4. BioMed Central 2023-07-20 /pmc/articles/PMC10357746/ /pubmed/37468982 http://dx.doi.org/10.1186/s13256-023-04043-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Lin, I-Fan
Shen, Hsiao-Chin
Lin, Shiou-Fu
Chang, Ho-Chuen
Chen, Tzu-Tao
Interstitial lung disease related to occupational hard metal exposure: two case reports
title Interstitial lung disease related to occupational hard metal exposure: two case reports
title_full Interstitial lung disease related to occupational hard metal exposure: two case reports
title_fullStr Interstitial lung disease related to occupational hard metal exposure: two case reports
title_full_unstemmed Interstitial lung disease related to occupational hard metal exposure: two case reports
title_short Interstitial lung disease related to occupational hard metal exposure: two case reports
title_sort interstitial lung disease related to occupational hard metal exposure: two case reports
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357746/
https://www.ncbi.nlm.nih.gov/pubmed/37468982
http://dx.doi.org/10.1186/s13256-023-04043-4
work_keys_str_mv AT linifan interstitiallungdiseaserelatedtooccupationalhardmetalexposuretwocasereports
AT shenhsiaochin interstitiallungdiseaserelatedtooccupationalhardmetalexposuretwocasereports
AT linshioufu interstitiallungdiseaserelatedtooccupationalhardmetalexposuretwocasereports
AT changhochuen interstitiallungdiseaserelatedtooccupationalhardmetalexposuretwocasereports
AT chentzutao interstitiallungdiseaserelatedtooccupationalhardmetalexposuretwocasereports