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Interstitial lung disease related to occupational hard metal exposure: two case reports
BACKGROUND: Hard metal lung disease (HMLD) is a relatively less known occupational interstitial lung disease, and instances of HMLD resulting from para-occupational exposure are rarely reported. CASE PRESENTATION: This paper presents two cases of interstitial lung disease caused by exposure to hard...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357746/ https://www.ncbi.nlm.nih.gov/pubmed/37468982 http://dx.doi.org/10.1186/s13256-023-04043-4 |
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author | Lin, I-Fan Shen, Hsiao-Chin Lin, Shiou-Fu Chang, Ho-Chuen Chen, Tzu-Tao |
author_facet | Lin, I-Fan Shen, Hsiao-Chin Lin, Shiou-Fu Chang, Ho-Chuen Chen, Tzu-Tao |
author_sort | Lin, I-Fan |
collection | PubMed |
description | BACKGROUND: Hard metal lung disease (HMLD) is a relatively less known occupational interstitial lung disease, and instances of HMLD resulting from para-occupational exposure are rarely reported. CASE PRESENTATION: This paper presents two cases of interstitial lung disease caused by exposure to hard metal. The first case involves a 37-year-old Taiwanese man who had worked at a grinder station for hard metal materials for 12 years without respiratory protective equipment. He experienced a dry cough and exertional dyspnea, and his chest imaging and pathology findings were consistent with the features of usual interstitial pneumonia. Analysis of his lung tissue revealed the presence of tungsten and cobalt. The second case involves a 68-year-old Taiwanese woman, the mother of the first patient, who had hand-washed her son’s workwear. She experienced a dry cough and had similar imaging findings to her son. After her son left his job, they both exhibited improved symptoms and lung functions with nintedanib treatment. These findings suggest a diagnosis of HMLD and interstitial lung disease resulting from para-occupational exposure to hard metal dust. CONCLUSIONS: The diagnosis of HMLD relies on obtaining a detailed occupational exposure history. If HMLD is diagnosed, discontinuing exposing to hard metal dusts can lead to improved lung function. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13256-023-04043-4. |
format | Online Article Text |
id | pubmed-10357746 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-103577462023-07-21 Interstitial lung disease related to occupational hard metal exposure: two case reports Lin, I-Fan Shen, Hsiao-Chin Lin, Shiou-Fu Chang, Ho-Chuen Chen, Tzu-Tao J Med Case Rep Case Report BACKGROUND: Hard metal lung disease (HMLD) is a relatively less known occupational interstitial lung disease, and instances of HMLD resulting from para-occupational exposure are rarely reported. CASE PRESENTATION: This paper presents two cases of interstitial lung disease caused by exposure to hard metal. The first case involves a 37-year-old Taiwanese man who had worked at a grinder station for hard metal materials for 12 years without respiratory protective equipment. He experienced a dry cough and exertional dyspnea, and his chest imaging and pathology findings were consistent with the features of usual interstitial pneumonia. Analysis of his lung tissue revealed the presence of tungsten and cobalt. The second case involves a 68-year-old Taiwanese woman, the mother of the first patient, who had hand-washed her son’s workwear. She experienced a dry cough and had similar imaging findings to her son. After her son left his job, they both exhibited improved symptoms and lung functions with nintedanib treatment. These findings suggest a diagnosis of HMLD and interstitial lung disease resulting from para-occupational exposure to hard metal dust. CONCLUSIONS: The diagnosis of HMLD relies on obtaining a detailed occupational exposure history. If HMLD is diagnosed, discontinuing exposing to hard metal dusts can lead to improved lung function. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13256-023-04043-4. BioMed Central 2023-07-20 /pmc/articles/PMC10357746/ /pubmed/37468982 http://dx.doi.org/10.1186/s13256-023-04043-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report Lin, I-Fan Shen, Hsiao-Chin Lin, Shiou-Fu Chang, Ho-Chuen Chen, Tzu-Tao Interstitial lung disease related to occupational hard metal exposure: two case reports |
title | Interstitial lung disease related to occupational hard metal exposure: two case reports |
title_full | Interstitial lung disease related to occupational hard metal exposure: two case reports |
title_fullStr | Interstitial lung disease related to occupational hard metal exposure: two case reports |
title_full_unstemmed | Interstitial lung disease related to occupational hard metal exposure: two case reports |
title_short | Interstitial lung disease related to occupational hard metal exposure: two case reports |
title_sort | interstitial lung disease related to occupational hard metal exposure: two case reports |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357746/ https://www.ncbi.nlm.nih.gov/pubmed/37468982 http://dx.doi.org/10.1186/s13256-023-04043-4 |
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