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Diagnostic value of D-dimer for lower extremity deep venous thrombosis caused by rib fracture: a retrospective study
OBJECTIVE: This study aimed to investigate the role of D-dimer in the diagnosis of lower extremity deep venous thrombosis (DVT) in patients with rib fractures. METHOD: Retrospective analysis was conducted on the clinical data of 499 patients with rib fractures who were admitted to the Third Hospital...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357766/ https://www.ncbi.nlm.nih.gov/pubmed/37475021 http://dx.doi.org/10.1186/s13018-023-03997-x |
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author | Feng, Lei Xie, Zexin Zhou, Xuetao Hou, Chunjuan Liang, Zheng Lu, Huiqing Liu, Lili Zhang, Dongsheng |
author_facet | Feng, Lei Xie, Zexin Zhou, Xuetao Hou, Chunjuan Liang, Zheng Lu, Huiqing Liu, Lili Zhang, Dongsheng |
author_sort | Feng, Lei |
collection | PubMed |
description | OBJECTIVE: This study aimed to investigate the role of D-dimer in the diagnosis of lower extremity deep venous thrombosis (DVT) in patients with rib fractures. METHOD: Retrospective analysis was conducted on the clinical data of 499 patients with rib fractures who were admitted to the Third Hospital of Shijiazhuang between October 2020 and September 2021. These patients were divided into the DVT and the non-DVT groups. D-dimer levels were compared between the two groups at 24, 48, and 72 h after the injury. Receiver operating characteristic curves were utilized to evaluate the diagnostic efficacy of dynamically monitoring changes in D-dimer for DVT. RESULTS: The D-dimer levels in the DVT group were significantly higher than those in the non-DVT group at 24, 48, and 72 h after the injury. The area under the curve values for predicting DVT based on D-dimer level at 24, 48, and 72 h after injury in patients with rib fractures were 0.788, 0.605, and 0.568, respectively. CONCLUSION: Detecting D-dimer levels 24 h after the injury can enhance diagnostic efficacy and sensitivity for DVT, thereby reducing the rate of missed diagnoses, which is of great clinical value. |
format | Online Article Text |
id | pubmed-10357766 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-103577662023-07-21 Diagnostic value of D-dimer for lower extremity deep venous thrombosis caused by rib fracture: a retrospective study Feng, Lei Xie, Zexin Zhou, Xuetao Hou, Chunjuan Liang, Zheng Lu, Huiqing Liu, Lili Zhang, Dongsheng J Orthop Surg Res Research Article OBJECTIVE: This study aimed to investigate the role of D-dimer in the diagnosis of lower extremity deep venous thrombosis (DVT) in patients with rib fractures. METHOD: Retrospective analysis was conducted on the clinical data of 499 patients with rib fractures who were admitted to the Third Hospital of Shijiazhuang between October 2020 and September 2021. These patients were divided into the DVT and the non-DVT groups. D-dimer levels were compared between the two groups at 24, 48, and 72 h after the injury. Receiver operating characteristic curves were utilized to evaluate the diagnostic efficacy of dynamically monitoring changes in D-dimer for DVT. RESULTS: The D-dimer levels in the DVT group were significantly higher than those in the non-DVT group at 24, 48, and 72 h after the injury. The area under the curve values for predicting DVT based on D-dimer level at 24, 48, and 72 h after injury in patients with rib fractures were 0.788, 0.605, and 0.568, respectively. CONCLUSION: Detecting D-dimer levels 24 h after the injury can enhance diagnostic efficacy and sensitivity for DVT, thereby reducing the rate of missed diagnoses, which is of great clinical value. BioMed Central 2023-07-20 /pmc/articles/PMC10357766/ /pubmed/37475021 http://dx.doi.org/10.1186/s13018-023-03997-x Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Feng, Lei Xie, Zexin Zhou, Xuetao Hou, Chunjuan Liang, Zheng Lu, Huiqing Liu, Lili Zhang, Dongsheng Diagnostic value of D-dimer for lower extremity deep venous thrombosis caused by rib fracture: a retrospective study |
title | Diagnostic value of D-dimer for lower extremity deep venous thrombosis caused by rib fracture: a retrospective study |
title_full | Diagnostic value of D-dimer for lower extremity deep venous thrombosis caused by rib fracture: a retrospective study |
title_fullStr | Diagnostic value of D-dimer for lower extremity deep venous thrombosis caused by rib fracture: a retrospective study |
title_full_unstemmed | Diagnostic value of D-dimer for lower extremity deep venous thrombosis caused by rib fracture: a retrospective study |
title_short | Diagnostic value of D-dimer for lower extremity deep venous thrombosis caused by rib fracture: a retrospective study |
title_sort | diagnostic value of d-dimer for lower extremity deep venous thrombosis caused by rib fracture: a retrospective study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357766/ https://www.ncbi.nlm.nih.gov/pubmed/37475021 http://dx.doi.org/10.1186/s13018-023-03997-x |
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