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Role of CD9 Sensing, AI, and Exosomes in Cellular Communication of Cancer
Exosomes are small membrane-bound vesicles that are released by various types of cells, including cancer cells, and play a role in intercellular communication. CD9 is a protein that is involved in cell signaling and adhesion. It is found on the surface of various cells, including cancer cells, and h...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357966/ https://www.ncbi.nlm.nih.gov/pubmed/37475778 http://dx.doi.org/10.23937/2469-570X/1410079 |
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author | Baghban, Neda Kodam, Sai Priyanka Ullah, Mujib |
author_facet | Baghban, Neda Kodam, Sai Priyanka Ullah, Mujib |
author_sort | Baghban, Neda |
collection | PubMed |
description | Exosomes are small membrane-bound vesicles that are released by various types of cells, including cancer cells, and play a role in intercellular communication. CD9 is a protein that is involved in cell signaling and adhesion. It is found on the surface of various cells, including cancer cells, and has been implicated in the communication between cancer cells and their microenvironment. Exosomes are small membrane-bound vesicles that are released by cells and contain various bioactive molecules, such as proteins, lipids, and nucleic acids. Exosomes have been shown to play a role in intercellular communication, and they have been implicated in the progression of cancer. There is evidence to suggest that CD9 is involved in the packaging and release of exosomes by cancer cells. CD9 has been shown to be important for the formation of tetraspanin-enriched microdomains (TEMs) on the surface of exosomes. These TEMs are thought to be important for the sorting and packaging of specific molecules into exosomes. In summary, CD9 appears to play an important role in the communication between cancer cells and their microenvironment via exosomes. The precise mechanisms by which CD9 mediates this communication are still being investigated, but the involvement of CD9 in exosome packaging and uptake suggests that it may be a promising target for the development of novel cancer therapies. Furthermore, CD9 has been shown to be involved in the uptake of exosomes by recipient cells. For example, studies have shown that CD9-positive exosomes released by cancer cells can be taken up by other cancer cells, leading to the transfer of oncogenic molecules and the promotion of cancer progression. |
format | Online Article Text |
id | pubmed-10357966 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
record_format | MEDLINE/PubMed |
spelling | pubmed-103579662023-07-20 Role of CD9 Sensing, AI, and Exosomes in Cellular Communication of Cancer Baghban, Neda Kodam, Sai Priyanka Ullah, Mujib Int J Stem Cell Res Ther Article Exosomes are small membrane-bound vesicles that are released by various types of cells, including cancer cells, and play a role in intercellular communication. CD9 is a protein that is involved in cell signaling and adhesion. It is found on the surface of various cells, including cancer cells, and has been implicated in the communication between cancer cells and their microenvironment. Exosomes are small membrane-bound vesicles that are released by cells and contain various bioactive molecules, such as proteins, lipids, and nucleic acids. Exosomes have been shown to play a role in intercellular communication, and they have been implicated in the progression of cancer. There is evidence to suggest that CD9 is involved in the packaging and release of exosomes by cancer cells. CD9 has been shown to be important for the formation of tetraspanin-enriched microdomains (TEMs) on the surface of exosomes. These TEMs are thought to be important for the sorting and packaging of specific molecules into exosomes. In summary, CD9 appears to play an important role in the communication between cancer cells and their microenvironment via exosomes. The precise mechanisms by which CD9 mediates this communication are still being investigated, but the involvement of CD9 in exosome packaging and uptake suggests that it may be a promising target for the development of novel cancer therapies. Furthermore, CD9 has been shown to be involved in the uptake of exosomes by recipient cells. For example, studies have shown that CD9-positive exosomes released by cancer cells can be taken up by other cancer cells, leading to the transfer of oncogenic molecules and the promotion of cancer progression. 2023 2023-05-20 /pmc/articles/PMC10357966/ /pubmed/37475778 http://dx.doi.org/10.23937/2469-570X/1410079 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Article Baghban, Neda Kodam, Sai Priyanka Ullah, Mujib Role of CD9 Sensing, AI, and Exosomes in Cellular Communication of Cancer |
title | Role of CD9 Sensing, AI, and Exosomes in Cellular Communication of Cancer |
title_full | Role of CD9 Sensing, AI, and Exosomes in Cellular Communication of Cancer |
title_fullStr | Role of CD9 Sensing, AI, and Exosomes in Cellular Communication of Cancer |
title_full_unstemmed | Role of CD9 Sensing, AI, and Exosomes in Cellular Communication of Cancer |
title_short | Role of CD9 Sensing, AI, and Exosomes in Cellular Communication of Cancer |
title_sort | role of cd9 sensing, ai, and exosomes in cellular communication of cancer |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357966/ https://www.ncbi.nlm.nih.gov/pubmed/37475778 http://dx.doi.org/10.23937/2469-570X/1410079 |
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