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CRISPR-based gene editing of non-homologous end joining factors biases DNA repair pathway choice toward single-strand annealing in Aedes aegypti

To maintain genome stability, eukaryotic cells orchestrate DNA repair pathways to process DNA double-strand breaks (DSBs) that result from diverse developmental or environmental stimuli. Bias in the selection of DSB repair pathways, either non-homologous end joining (NHEJ) or homology-directed repai...

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Detalles Bibliográficos
Autores principales:	Chae, Keun, Overcash, Justin M., Dawson, Chanell, Valentin, Collin, Tsujimoto, Hitoshi, Myles, Kevin M., Adelman, Zach N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357993/ https://www.ncbi.nlm.nih.gov/pubmed/37475832 http://dx.doi.org/10.1016/j.crbiot.2023.100133

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