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PIK3R3 is upregulated in liver cancer and activates Akt signaling to control cancer growth by regulation of CDKN1C and SMC1A

BACKGROUND: Liver cancer is a highly malignant disease and the third leading cause of cancer death worldwide. Abnormal activation of PI3K/Akt signaling is common in cancer, but whether phosphoinositide‐3‐kinase regulatory subunit 3 (PIK3R3) plays a role in liver cancer is largely unexplored. METHODS...

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Detalles Bibliográficos
Autores principales: Lin, Weidong, Wang, Kunpeng, Mo, Jinggang, Wang, Liezhi, Song, Zhenshun, Jiang, Hao, Wang, Cong, Jin, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358214/
https://www.ncbi.nlm.nih.gov/pubmed/37212524
http://dx.doi.org/10.1002/cam4.6068