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The impact of preoperative total parenteral nutrition on the surgical complications of Crohn’s disease: A retrospective cohort study
BACKGROUND: Crohn’s disease (CD) is associated with malnutrition, an independent risk factor for surgical morbidity and mortality in more than 65% of patients, with a significant impact on disease outcomes. In this single-center retrospective cohort study, we aimed to investigate the impact of total...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358801/ https://www.ncbi.nlm.nih.gov/pubmed/36588367 http://dx.doi.org/10.4103/sjg.sjg_425_22 |
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author | Bin Traiki, Thamer A. Alshammari, Sulaiman A. Aljomah, Nadia A. Alsalouli, Monirah M. Altawil, Esraa S. Abdulla, Maha-Hamadien Alhassan, Noura S. Alkhayal, Khayal A. |
author_facet | Bin Traiki, Thamer A. Alshammari, Sulaiman A. Aljomah, Nadia A. Alsalouli, Monirah M. Altawil, Esraa S. Abdulla, Maha-Hamadien Alhassan, Noura S. Alkhayal, Khayal A. |
author_sort | Bin Traiki, Thamer A. |
collection | PubMed |
description | BACKGROUND: Crohn’s disease (CD) is associated with malnutrition, an independent risk factor for surgical morbidity and mortality in more than 65% of patients, with a significant impact on disease outcomes. In this single-center retrospective cohort study, we aimed to investigate the impact of total parenteral nutrition (TPN) on the surgical outcomes of patients with CD. METHODS: This study included patients with CD who underwent abdominal surgery. We compared patients who received preoperative total parenteral nutrition (TPN group) to those who did not (non-TPN group). Prolonged oral intolerance, albumin level <30 g/L, and body mass index <18.5 were the main indications for TPN. We evaluated postoperative surgical complications in both groups. RESULTS: Between January 2010 and October 2018, 169 eligible patients underwent abdominal surgery. The TPN and non-TPN groups included 40 and 129 patients, respectively. The mean albumin level was significantly lower in the TPN group (P = 0.013). Laparoscopic surgery was performed in 76.9% of the patients, with a conversion rate of 11.6%. Infectious and non-infectious complications developed in 8.9% and 16% of patients, respectively. Surgical complications were comparable between the groups (P >0.05). CONCLUSIONS: Despite oral intake intolerance and severe disease in the TPN group, the surgical complications were comparable between the groups. |
format | Online Article Text |
id | pubmed-10358801 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-103588012023-07-21 The impact of preoperative total parenteral nutrition on the surgical complications of Crohn’s disease: A retrospective cohort study Bin Traiki, Thamer A. Alshammari, Sulaiman A. Aljomah, Nadia A. Alsalouli, Monirah M. Altawil, Esraa S. Abdulla, Maha-Hamadien Alhassan, Noura S. Alkhayal, Khayal A. Saudi J Gastroenterol Original Article BACKGROUND: Crohn’s disease (CD) is associated with malnutrition, an independent risk factor for surgical morbidity and mortality in more than 65% of patients, with a significant impact on disease outcomes. In this single-center retrospective cohort study, we aimed to investigate the impact of total parenteral nutrition (TPN) on the surgical outcomes of patients with CD. METHODS: This study included patients with CD who underwent abdominal surgery. We compared patients who received preoperative total parenteral nutrition (TPN group) to those who did not (non-TPN group). Prolonged oral intolerance, albumin level <30 g/L, and body mass index <18.5 were the main indications for TPN. We evaluated postoperative surgical complications in both groups. RESULTS: Between January 2010 and October 2018, 169 eligible patients underwent abdominal surgery. The TPN and non-TPN groups included 40 and 129 patients, respectively. The mean albumin level was significantly lower in the TPN group (P = 0.013). Laparoscopic surgery was performed in 76.9% of the patients, with a conversion rate of 11.6%. Infectious and non-infectious complications developed in 8.9% and 16% of patients, respectively. Surgical complications were comparable between the groups (P >0.05). CONCLUSIONS: Despite oral intake intolerance and severe disease in the TPN group, the surgical complications were comparable between the groups. Wolters Kluwer - Medknow 2022-12-30 /pmc/articles/PMC10358801/ /pubmed/36588367 http://dx.doi.org/10.4103/sjg.sjg_425_22 Text en Copyright: © 2022 Saudi Journal of Gastroenterology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Bin Traiki, Thamer A. Alshammari, Sulaiman A. Aljomah, Nadia A. Alsalouli, Monirah M. Altawil, Esraa S. Abdulla, Maha-Hamadien Alhassan, Noura S. Alkhayal, Khayal A. The impact of preoperative total parenteral nutrition on the surgical complications of Crohn’s disease: A retrospective cohort study |
title | The impact of preoperative total parenteral nutrition on the surgical complications of Crohn’s disease: A retrospective cohort study |
title_full | The impact of preoperative total parenteral nutrition on the surgical complications of Crohn’s disease: A retrospective cohort study |
title_fullStr | The impact of preoperative total parenteral nutrition on the surgical complications of Crohn’s disease: A retrospective cohort study |
title_full_unstemmed | The impact of preoperative total parenteral nutrition on the surgical complications of Crohn’s disease: A retrospective cohort study |
title_short | The impact of preoperative total parenteral nutrition on the surgical complications of Crohn’s disease: A retrospective cohort study |
title_sort | impact of preoperative total parenteral nutrition on the surgical complications of crohn’s disease: a retrospective cohort study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358801/ https://www.ncbi.nlm.nih.gov/pubmed/36588367 http://dx.doi.org/10.4103/sjg.sjg_425_22 |
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