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TLR7/TLR8 activation and susceptibility genes synergize to breach gut barrier in a mouse model of lupus

BACKGROUND: Mounting evidence suggests that increased gut permeability, or leaky gut, and the resulting translocation of pathobionts or their metabolites contributes to the pathogenesis of Systemic Lupus Erythematosus. However, the mechanisms underlying the induction of gut leakage remain unclear. I...

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Detalles Bibliográficos
Autores principales:	Ma, Longhuan, Terrell, Morgan, Brown, Josephine, Castellanos Garcia, Abigail, Elshikha, Ahmed, Morel, Laurence
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358848/ https://www.ncbi.nlm.nih.gov/pubmed/37483626 http://dx.doi.org/10.3389/fimmu.2023.1187145

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