Influence of FGF4 and BMP4 on FGFR2 dynamics during the segregation of epiblast and primitive endoderm cells in the pre-implantation mouse embryo

Specification of the epiblast (EPI) and primitive endoderm (PE) in the mouse embryo involves fibroblast growth factor (FGF) signaling through the RAS/MAP kinase pathway. FGFR1 and FGFR2 are thought to mediate this signaling in the inner cell mass (ICM) of the mouse blastocyst and BMP signaling can a...

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Detalles Bibliográficos
Autores principales: Goissis, Marcelo D., Bradshaw, Brian, Posfai, Eszter, Rossant, Janet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358967/
https://www.ncbi.nlm.nih.gov/pubmed/37471320
http://dx.doi.org/10.1371/journal.pone.0279515

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