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Nanoplasmonic biosensors for precision medicine
Nanoplasmonic biosensors have a huge boost for precision medicine, which allows doctors to better understand diseases at the molecular level and to improve the earlier diagnosis and develop treatment programs. Unlike traditional biosensors, nanoplasmonic biosensors meet the global health industry’s...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359043/ https://www.ncbi.nlm.nih.gov/pubmed/37483272 http://dx.doi.org/10.3389/fchem.2023.1209744 |
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author | Xiao, Yiran Zhang, Zongming Yin, Shi Ma, Xingyi |
author_facet | Xiao, Yiran Zhang, Zongming Yin, Shi Ma, Xingyi |
author_sort | Xiao, Yiran |
collection | PubMed |
description | Nanoplasmonic biosensors have a huge boost for precision medicine, which allows doctors to better understand diseases at the molecular level and to improve the earlier diagnosis and develop treatment programs. Unlike traditional biosensors, nanoplasmonic biosensors meet the global health industry’s need for low-cost, rapid and portable aspects, while offering multiplexing, high sensitivity and real-time detection. In this review, we describe the common detection schemes used based on localized plasmon resonance (LSPR) and highlight three sensing classes based on LSPR. Then, we present the recent applications of nanoplasmonic in other sensing methods such as isothermal amplification, CRISPR/Cas systems, lab on a chip and enzyme-linked immunosorbent assay. The advantages of nanoplasmonic-based integrated sensing for multiple methods are discussed. Finally, we review the current applications of nanoplasmonic biosensors in precision medicine, such as DNA mutation, vaccine evaluation and drug delivery. The obstacles faced by nanoplasmonic biosensors and the current countermeasures are discussed. |
format | Online Article Text |
id | pubmed-10359043 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-103590432023-07-21 Nanoplasmonic biosensors for precision medicine Xiao, Yiran Zhang, Zongming Yin, Shi Ma, Xingyi Front Chem Chemistry Nanoplasmonic biosensors have a huge boost for precision medicine, which allows doctors to better understand diseases at the molecular level and to improve the earlier diagnosis and develop treatment programs. Unlike traditional biosensors, nanoplasmonic biosensors meet the global health industry’s need for low-cost, rapid and portable aspects, while offering multiplexing, high sensitivity and real-time detection. In this review, we describe the common detection schemes used based on localized plasmon resonance (LSPR) and highlight three sensing classes based on LSPR. Then, we present the recent applications of nanoplasmonic in other sensing methods such as isothermal amplification, CRISPR/Cas systems, lab on a chip and enzyme-linked immunosorbent assay. The advantages of nanoplasmonic-based integrated sensing for multiple methods are discussed. Finally, we review the current applications of nanoplasmonic biosensors in precision medicine, such as DNA mutation, vaccine evaluation and drug delivery. The obstacles faced by nanoplasmonic biosensors and the current countermeasures are discussed. Frontiers Media S.A. 2023-07-06 /pmc/articles/PMC10359043/ /pubmed/37483272 http://dx.doi.org/10.3389/fchem.2023.1209744 Text en Copyright © 2023 Xiao, Zhang, Yin and Ma. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Chemistry Xiao, Yiran Zhang, Zongming Yin, Shi Ma, Xingyi Nanoplasmonic biosensors for precision medicine |
title | Nanoplasmonic biosensors for precision medicine |
title_full | Nanoplasmonic biosensors for precision medicine |
title_fullStr | Nanoplasmonic biosensors for precision medicine |
title_full_unstemmed | Nanoplasmonic biosensors for precision medicine |
title_short | Nanoplasmonic biosensors for precision medicine |
title_sort | nanoplasmonic biosensors for precision medicine |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359043/ https://www.ncbi.nlm.nih.gov/pubmed/37483272 http://dx.doi.org/10.3389/fchem.2023.1209744 |
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