Cargando…

Locus specific endogenous retroviral expression associated with Alzheimer’s disease

INTRODUCTION: Human endogenous retroviruses (HERVs) are transcriptionally-active remnants of ancient retroviral infections that may play a role in Alzheimer’s disease. METHODS: We combined two, publicly available RNA-Seq datasets with a third, novel dataset for a total cohort of 103 patients with Al...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dawson, Tyson, Rentia, Uzma, Sanford, Jessie, Cruchaga, Carlos, Kauwe, John S. K., Crandall, Keith A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359044/ https://www.ncbi.nlm.nih.gov/pubmed/37484691 http://dx.doi.org/10.3389/fnagi.2023.1186470

Ejemplares similares

Natural history of the ERVWE1 endogenous retroviral locus
por: Bonnaud, Bertrand, et al.
Publicado: (2005)

Sex-specific aspects of endogenous retroviral insertion and deletion
por: Gemmell, Patrick, et al.
Publicado: (2013)

Involvement of the endogenous retroviral locus HERV-Fc1 on the human X-chromosome in multiple sclerosis
por: Nexø, Bjørn A, et al.
Publicado: (2011)

Alzheimer's disease alters oligodendrocytic glycolytic and ketolytic gene expression
por: Saito, Erin R., et al.
Publicado: (2021)

Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease
por: Tarawneh, Rawan, et al.
Publicado: (2022)

Validation of Variant Assembly Using HAPHPIPE with Next-Generation Sequence Data from Viruses
por: Gibson, Keylie M., et al.
Publicado: (2020)

HAPHPIPE: Haplotype Reconstruction and Phylodynamics for Deep Sequencing of Intrahost Viral Populations
por: Bendall, Matthew L, et al.
Publicado: (2020)

Expression of Human Endogenous Retroviruses in Systemic Lupus Erythematosus: Multiomic Integration With Gene Expression
por: Stearrett, Nathaniel, et al.
Publicado: (2021)

Haplotype-based association analysis of the MAPT locus in Late Onset Alzheimer's disease
por: Mukherjee, Odity, et al.
Publicado: (2007)

Use of Endogenous Retroviral Sequences (ERVs) and structural markers for retroviral phylogenetic inference and taxonomy
por: Jern, Patric, et al.
Publicado: (2005)

Unfixed Endogenous Retroviral Insertions in the Human Population
por: Marchi, Emanuele, et al.
Publicado: (2014)

Endogenous retroviral promoter exaptation in human cancer
por: Babaian, Artem, et al.
Publicado: (2016)

Retroviral vectors encoding ADA regulatory locus control region provide enhanced T-cell-specific transgene expression
por: Trinh, Alice T, et al.
Publicado: (2009)

The Neuroanatomy of the Reticular Nucleus Locus Coeruleus in Alzheimer’s Disease
por: Giorgi, Filippo S., et al.
Publicado: (2017)

RAB10: an Alzheimer’s disease resilience locus and potential drug target
por: Tavana, Justina P, et al.
Publicado: (2018)

Embryonic expression of endogenous retroviral RNAs in somatic tissues adjacent to the Oikopleura germline
por: Henriet, Simon, et al.
Publicado: (2015)

High Expression of Endogenous Retroviral Envelope Gene in the Equine Fetal Part of the Placenta
por: Stefanetti, Valentina, et al.
Publicado: (2016)

Identification of endogenous retroviral reading frames in the human genome
por: Villesen, Palle, et al.
Publicado: (2004)

Activation of antigen-presenting cells by endogenous retroviral RNA
por: Moyes, D, et al.
Publicado: (2005)

TIP60 represses activation of endogenous retroviral elements
por: Rajagopalan, Deepa, et al.
Publicado: (2018)

Genetic Association of Multiple Sclerosis with the Marker rs391745 near the Endogenous Retroviral Locus HERV-Fc1: Analysis of Disease Subtypes
por: Hansen, Bettina, et al.
Publicado: (2011)

HIV-1 infection activates endogenous retroviral promoters regulating antiviral gene expression
por: Srinivasachar Badarinarayan, Smitha, et al.
Publicado: (2020)

A contaminant-free assessment of Endogenous Retroviral RNA in human plasma
por: Karamitros, Timokratis, et al.
Publicado: (2016)

Widely variable endogenous retroviral methylation levels in human placenta
por: Reiss, Daphne, et al.
Publicado: (2007)

A revised nomenclature for transcribed human endogenous retroviral loci
por: Mayer, Jens, et al.
Publicado: (2011)

Two endogenous retroviral loci appear to contribute to Multiple Sclerosis
por: Nexø, Bjørn A., et al.
Publicado: (2016)

Characterization of the fusion core in zebrafish endogenous retroviral envelope protein
por: Shi, Jian, et al.
Publicado: (2015)

Expression of selected human endogenous retroviral sequences in skin and peripheral blood mononuclear cells in morphea
por: Kowalczyk, Michał J., et al.
Publicado: (2012)

Evaluation of Gene-Based Family-Based Methods to Detect Novel Genes Associated With Familial Late Onset Alzheimer Disease
por: Fernández, Maria V., et al.
Publicado: (2018)

New insights into retroviral Gag–Gag and Gag–membrane interactions
por: Maldonado, José O., et al.
Publicado: (2014)

Secreted endogenous macrosomes reduce Aβ burden and ameliorate Alzheimer’s disease
por: Wang, Cunli, et al.
Publicado: (2023)

Stably integrated and expressed retroviral sequences can influence nuclear location and chromatin condensation of the integration locus
por: Nagel, Jens, et al.
Publicado: (2012)

Functional specificity of the locus coeruleus-norepinephrine system in the attentional networks
por: Ambrosini, Ettore, et al.
Publicado: (2013)

Endogenous non-retroviral elements in genomes of Aedes mosquitoes and vector competence
por: Houé, Vincent, et al.
Publicado: (2019)

Daxx maintains endogenous retroviral silencing and restricts cellular plasticity in vivo
por: Wasylishen, Amanda R., et al.
Publicado: (2020)

Endogenous Retroviral Elements Generate Pathologic Neutrophils in Pulmonary Arterial Hypertension
por: Taylor, Shalina, et al.
Publicado: (2022)

Co-option of a non-retroviral endogenous viral element in planthoppers
por: Huang, Hai-Jian, et al.
Publicado: (2023)

Locus specific human endogenous retroviruses reveal new lymphoma subtypes
por: Singh, Bhavya, et al.
Publicado: (2023)

Differential expression of an endogenous retroviral element [HERV-K(HML-6)] is associated with reduced survival in glioblastoma patients
por: Shah, Ashish H., et al.
Publicado: (2022)

A Systematic Review of Expression and Immunogenicity of Human Endogenous Retroviral Proteins in Cancer and Discussion of Therapeutic Approaches
por: Müller, Mikkel Dons, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qc11dki8n2qagffuk39fmv448q