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Retrospective analysis of fungemia among children in Anka General Hospital, Nigeria, from October 2018 to November 2021: a case series

Yeast-related bloodstream infections (BSIs) in pediatric patients are associated with severe acute malnutrition (SAM), hematological/oncological malignancies and admission to an intensive care unit. These infections are rarely described from low- and middle-income countries. We describe a case serie...

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Detalles Bibliográficos
Autores principales: Olubiyo, Ruth, Chukwumeze, Frederick, Lawal, Abdulhakeem Mohammed, Oloruntuyi, Gbemisola, Musoka, Honore, Augustine, Nwogu Ahamba, Abdullahi, Ibrahim, Shehu, Ismail, Egwuenu, Abiodun, Clezy, Kate, Oluyide, Bukola, Gomez, Diana, Sherlock, Mark, Lenglet, Annick, Repetto, Ernestina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359058/
https://www.ncbi.nlm.nih.gov/pubmed/37484557
http://dx.doi.org/10.1093/omcr/omad071
Descripción
Sumario:Yeast-related bloodstream infections (BSIs) in pediatric patients are associated with severe acute malnutrition (SAM), hematological/oncological malignancies and admission to an intensive care unit. These infections are rarely described from low- and middle-income countries. We describe a case series of pediatric patients diagnosed with severe sepsis and yeast isolated from their blood culture in a conflict-affected area of Nigeria from October 2018 to November 2021. We identified 20 patients with yeast BSIs, among whom 17 were also diagnosed with SAM. We recommend the inclusion of antifungal treatment for empiric treatment guidelines for children with SAM and severe sepsis in similar settings.