CRISPR-Cas-amplified urinary biomarkers for multiplexed and portable cancer diagnostics

Synthetic biomarkers, bioengineered sensors that generate molecular reporters in diseased microenvironments, represent an emerging paradigm in precision diagnostics. Despite the utility of DNA barcodes as a multiplexing tool, their susceptibility to nucleases in vivo has limited their utility. Here...

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Detalles Bibliográficos
Autores principales: Hao, Liangliang, Zhao, Renee T., Welch, Nicole L., Tan, Edward Kah Wei, Zhong, Qian, Harzallah, Nour Saida, Ngambenjawong, Chayanon, Ko, Henry, Fleming, Heather E., Sabeti, Pardis C., Bhatia, Sangeeta N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359190/
https://www.ncbi.nlm.nih.gov/pubmed/37095220
http://dx.doi.org/10.1038/s41565-023-01372-9

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