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Aryl-functionalised α,α′-Trehalose 6,6′-Glycolipid Induces Mincle-independent Pyroptotic Cell Death

α,α′-Trehalose 6,6′-glycolipids have long been known for their immunostimulatory properties. The adjuvanticity of α,α′-trehalose 6,6′-glycolipids is mediated by signalling through the macrophage inducible C-type lectin (Mincle) and the induction of an inflammatory response. Herein, we present an ary...

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Detalles Bibliográficos
Autores principales: Kodar, Kristel, Dangerfield, Emma M., Foster, Amy J., Forsythe, Devlin, Ishizuka, Shigenari, McConnell, Melanie J., Yamasaki, Sho, Timmer, Mattie S. M., Stocker, Bridget L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359228/
https://www.ncbi.nlm.nih.gov/pubmed/37140682
http://dx.doi.org/10.1007/s10753-023-01814-5

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