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Diagnostic performance of SARC-F and SARC-CalF in screening for sarcopenia in older adults in Northern Brazil

To compare the performance of SARC-F and SARC-CalF as screening tools for sarcopenia. Cross-sectional study with a convenience sample of 312 community-dwelling older people. Sarcopenia was defined as low handgrip strength (HGS) or low gait speed (GS ≤ 0.8 m/s). HGS was measured by dynamometry and GS...

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Autores principales: Barreto de Lima, Alex, dos Santos Ribeiro, Gustavo, Henriques-Neto, Duarte, Rúbio Gouveia, Élvio, Baptista, Fátima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359260/
https://www.ncbi.nlm.nih.gov/pubmed/37474595
http://dx.doi.org/10.1038/s41598-023-39002-y
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author Barreto de Lima, Alex
dos Santos Ribeiro, Gustavo
Henriques-Neto, Duarte
Rúbio Gouveia, Élvio
Baptista, Fátima
author_facet Barreto de Lima, Alex
dos Santos Ribeiro, Gustavo
Henriques-Neto, Duarte
Rúbio Gouveia, Élvio
Baptista, Fátima
author_sort Barreto de Lima, Alex
collection PubMed
description To compare the performance of SARC-F and SARC-CalF as screening tools for sarcopenia. Cross-sectional study with a convenience sample of 312 community-dwelling older people. Sarcopenia was defined as low handgrip strength (HGS) or low gait speed (GS ≤ 0.8 m/s). HGS was measured by dynamometry and GS by the 4-m walking speed test. For HGS, six criteria (C) were used to identify sarcopenia in men/women: C(I): < 27 kg/16 kg; C(II): < 35.5 kg/20.0 kg; C(III): grip over body mass index < 1.05/< 0.79; C(IV): grip strength over total body fat < 1.66/< 0.65; C(V): grip over bodyweight < 0.45/< 0.34; C(VI): < 27 kg/16 kg and low skeletal muscle mass index (SMMI); C(I) and C(VI) defined according to the European Working Group on sarcopenia in older people and the rest according to the sarcopenia definition and outcomes Consortium. For sarcopenia screening, the SARC-F (≥ 4 points) and the SARC-CalF (≥ 11 points) were used. The kappa analysis revealed no agreement between the SARC-F and the various criteria for the identification of sarcopenia in men. The same lack of agreement was observed in women with some exceptions: C(I) = 0.161 ± 0.074, p = 0.020; GS = 0.209 ± 0.076, p = 0.003. Concerning the Cohen’s kappa between the SARC-Calf and the reference criteria of sarcopenia, the following coefficients were observed as significant for women: C(I) = 0.201 ± 0.069, p = 0.003; C(II) = 0.186 ± 0.064, p = 0.005; GS = 0.273 ± 0.068, p = 0.0001; and for men: C(II) = 0.139 ± 0.053, p = 0.021; GS = 0.223 ± 0.099, p = 0.011. ROC curves revealed the SARC-Calf with acceptable discrimination and reasonable sarcopenia predictive capacity considering a cutoff value of 10.5 in both men (AUC: 67.5%, p = 0.022; Se = 52.9%; Sp = 76.8%) and women (AUC: 72.4%, p < 0.001; Se = 63%; Sp = 68.5%) concerning GS. The SARC-CalF performed better than the SARC-F for screening sarcopenia in the population ≥ 60 years of age in the Amazonas, measured through walking slowness.
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spelling pubmed-103592602023-07-22 Diagnostic performance of SARC-F and SARC-CalF in screening for sarcopenia in older adults in Northern Brazil Barreto de Lima, Alex dos Santos Ribeiro, Gustavo Henriques-Neto, Duarte Rúbio Gouveia, Élvio Baptista, Fátima Sci Rep Article To compare the performance of SARC-F and SARC-CalF as screening tools for sarcopenia. Cross-sectional study with a convenience sample of 312 community-dwelling older people. Sarcopenia was defined as low handgrip strength (HGS) or low gait speed (GS ≤ 0.8 m/s). HGS was measured by dynamometry and GS by the 4-m walking speed test. For HGS, six criteria (C) were used to identify sarcopenia in men/women: C(I): < 27 kg/16 kg; C(II): < 35.5 kg/20.0 kg; C(III): grip over body mass index < 1.05/< 0.79; C(IV): grip strength over total body fat < 1.66/< 0.65; C(V): grip over bodyweight < 0.45/< 0.34; C(VI): < 27 kg/16 kg and low skeletal muscle mass index (SMMI); C(I) and C(VI) defined according to the European Working Group on sarcopenia in older people and the rest according to the sarcopenia definition and outcomes Consortium. For sarcopenia screening, the SARC-F (≥ 4 points) and the SARC-CalF (≥ 11 points) were used. The kappa analysis revealed no agreement between the SARC-F and the various criteria for the identification of sarcopenia in men. The same lack of agreement was observed in women with some exceptions: C(I) = 0.161 ± 0.074, p = 0.020; GS = 0.209 ± 0.076, p = 0.003. Concerning the Cohen’s kappa between the SARC-Calf and the reference criteria of sarcopenia, the following coefficients were observed as significant for women: C(I) = 0.201 ± 0.069, p = 0.003; C(II) = 0.186 ± 0.064, p = 0.005; GS = 0.273 ± 0.068, p = 0.0001; and for men: C(II) = 0.139 ± 0.053, p = 0.021; GS = 0.223 ± 0.099, p = 0.011. ROC curves revealed the SARC-Calf with acceptable discrimination and reasonable sarcopenia predictive capacity considering a cutoff value of 10.5 in both men (AUC: 67.5%, p = 0.022; Se = 52.9%; Sp = 76.8%) and women (AUC: 72.4%, p < 0.001; Se = 63%; Sp = 68.5%) concerning GS. The SARC-CalF performed better than the SARC-F for screening sarcopenia in the population ≥ 60 years of age in the Amazonas, measured through walking slowness. Nature Publishing Group UK 2023-07-20 /pmc/articles/PMC10359260/ /pubmed/37474595 http://dx.doi.org/10.1038/s41598-023-39002-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Barreto de Lima, Alex
dos Santos Ribeiro, Gustavo
Henriques-Neto, Duarte
Rúbio Gouveia, Élvio
Baptista, Fátima
Diagnostic performance of SARC-F and SARC-CalF in screening for sarcopenia in older adults in Northern Brazil
title Diagnostic performance of SARC-F and SARC-CalF in screening for sarcopenia in older adults in Northern Brazil
title_full Diagnostic performance of SARC-F and SARC-CalF in screening for sarcopenia in older adults in Northern Brazil
title_fullStr Diagnostic performance of SARC-F and SARC-CalF in screening for sarcopenia in older adults in Northern Brazil
title_full_unstemmed Diagnostic performance of SARC-F and SARC-CalF in screening for sarcopenia in older adults in Northern Brazil
title_short Diagnostic performance of SARC-F and SARC-CalF in screening for sarcopenia in older adults in Northern Brazil
title_sort diagnostic performance of sarc-f and sarc-calf in screening for sarcopenia in older adults in northern brazil
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359260/
https://www.ncbi.nlm.nih.gov/pubmed/37474595
http://dx.doi.org/10.1038/s41598-023-39002-y
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